Recombinant human Langerin/CD207 protein | NKMAX ATGP3047 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human Langerin/CD207 protein

catalog :

ATGP3047

quantity :

20 ug

price :

80 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human Langerin/CD207 protein

Domain :

65-328aa

Catalog number (SKU) :

ATGP3047

NCBI :

NP_056532

Description :

CD207 also known as C-type lectin domain family 4 member K. is expressed in Langerhans cells which are immature dendritic cells of the epidermis and mucosa. Additionally it's known by the name C-type lectin domain family 4 member K (CD antigen CD207). It is also expressed in several other dendritic cell types including dermal CD103+ DCs and splenic CD8+ DCs. Langerin is localized in the Birbeck granules, organelles present in the cytoplasm of Langerhans cells and consisting of superimposed and zippered membranes. It is a C-type lectin with mannose binding specificity, and it has been proposed that mannose binding by this protein leads to internalization of antigen into Birbeck granules and providing access to a nonclassical antigen-processing pathway. Recombinant human CD207, fused to His-tag at N-terminus, was expressed in E. coli.

Alternative Names :

C-type lectin domain family 4 member K, C-type lectin domain family 4 member K, CLEC4K

Concentration :

1mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Feinberg H., et al. (2013) J. Biol. Chem. 288 (52), 36762-36771;; Lauc G., et al. (2013) PLoS Genet. 9 (1), E1003225;;

Purity :

> 85% by SDS-PAGE

Applications :

SDS-PAGE,Denatured

Antigen Species :

Human

Gene Category :

Metabolism

Molecular Weight :

32.2 kDa (287aa)

Amino Acid Sequence :

MGSSHHHHHH SSGLVPRGSH MGSPRFMGTI SDVKTNVQLL KGRVDNISTL DSEIKKNSDG MEAAGVQIQM VNESLGYVRS QFLKLKTSVE KANAQIQILT RSWEEVSTLN AQIPELKSDL EKASALNTKI RALQGSLENM SKLLKRQNDI LQVVSQGWKY FKGNFYYFSL IPKTWYSAEQ FCVSRNSHLT SVTSESEQEF LYKTAGGLIY WIGLTKAGME GDWSWVDDTP FNKVQSARFW IPGEPNNAGN NEHCGNIKAP SLQAWNDAPC DKTFLFICKR PYVPSEP

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

Q9UJ71

Internal Search Terms :

Langerin, CD207, C-type lectin domain family 4 member K, C-type lectin domain family 4 member K, CLEC4K,ATGP3047-10ug,ATGP3047-20ug,ATGP3047-50ug,ATGP3047-100ug,ATGP3047-250ug,ATGP3047-500ug,ATGP3047-1mg,ATGP3047-10,ATGP3047-20,ATGP3047-50,ATGP3047-100,ATGP3047-250,ATGP3047-500,ATGP3047-1

more info or order :

NKMAX product webpage