product summary
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company name :
NKMAX
product type :
protein
product name :
Recombinant human TIMP-1 protein
catalog :
ATGP3013
quantity :
20 ug
price :
80 USD
more info or order :
NKMAX product webpage
product information
Product Type :
Proteins
Item Name :
Recombinant human TIMP-1 protein
Domain :
24-207aa
Catalog number (SKU) :
ATGP3013
NCBI :
NP_003245
Description :
TIMP1 also known as metalloproteinase inhibitor 1. The matrix metalloproteinases are inhibited by specific endogenous tissue inhibitors of metalloproteinases (TIMPs), which comprise a family of four protease inhibitors: TIMP1, TIMP2, TIMP3 and TIMP4. Overall, all MMPs are inhibited by TIMPs once they are activated but the gelatinases (MMP-2 and MMP-9) can form complexes with TIMPs when the enzymes are in the latent form. The complex of latent MMP-2 (pro-MMP-2) with TIMP-2 serves to facilitate the activation of pro-MMP-2 at the cell surface by MT1-MMP (MMP-14), a membrane-anchored MMP. The role of the pro-MMP-9/TIMP-1 complex is still unknown. Recombinant human TIMP1, fused to His-tag at N-terminus, was expressed in E. coli.
Alternative Names :
Metalloproteinase inhibitor 1, EPA, EPO, HCI, CLGI, TIMP
Concentration :
0.25mg/ml (determined by Bradford assay)
Formulation :
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Brew K., et al. (2000) Biochim Biophys Acta 1477 (1-2): 267-83.
Purity :
> 90% by SDS-PAGE
Applications :
SDS-PAGE,Denatured
Antigen Species :
Human
Gene Category :
Cardiovascular
Molecular Weight :
23 kDa (205aa)
Amino Acid Sequence :
MGSSHHHHHH SSGLVPRGSH MCTCVPPHPQ TAFCNSDLVI RAKFVGTPEV NQTTLYQRYE IKMTKMYKGF QALGDAADIR FVYTPAMESV CGYFHRSHNR SEEFLIAGKL QDGLLHITTC SFVAPWNSLS LAQRRGFTKT YTVGCEECTV FPCLSIPCKL QSGTHCLWTD QLLQGSEKGF QSRHLACLPR EPGLCTWQSL RSQIA
Tag :
His-Tag
Expression System :
E.coli
Product Type Name :
Recombinant Protein
UniProt No. :
P01033
Internal Search Terms :
TIMP1, Metalloproteinase inhibitor 1, EPA, EPO, HCI, CLGI, TIMP,ATGP3013-10ug,ATGP3013-20ug,ATGP3013-50ug,ATGP3013-100ug,ATGP3013-250ug,ATGP3013-500ug,ATGP3013-1mg,ATGP3013-10,ATGP3013-20,ATGP3013-50,ATGP3013-100,ATGP3013-250,ATGP3013-500,ATGP3013-1
more info or order :
NKMAX product webpage
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.