product summary
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company name :
NKMAX
product type :
protein
product name :
Recombinant human PTDSR/JMJD6 protein
catalog :
ATGP2999
quantity :
10 ug
price :
105 USD
more info or order :
product information
Product Type :
Proteins
Item Name :
Recombinant human PTDSR/JMJD6 protein
Domain :
1-414aa
Catalog number (SKU) :
ATGP2999
NCBI :
NP_001074930
Description :
JMJD6 also known as bifunctional arginine demethylase and lysyl-hydroxylase JMJD6. JMJD6 acts as a lysyl-hydroxylase that catalyzes 5-hydroxylation on specific lysine residues of target proteins such as u2AF2/u2AF65 and LuC7L2, as a regulator of RNA splicing by mediating 5-hydroxylation of u2AF2/u2AF65, affecting the pre-mRNA splicing activity of u2AF2/u2AF65. In addition to peptidyl-lysine 5-dioxygenase activity, may act as an RNA hydroxylase, as suggested by its ability to bind single strand RNA. Also acts as an arginine demethylase which demethylates histone H3 at 'Arg-2' (H3R2me) and histone H4 at 'Arg-3' (H4R3me), thereby playing a role in histone code. Recombinant human JMJD6, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Alternative Names :
Jumonji domain containing 6, Arginine demethylase and lysine hydroxylase, Phosphatidylserine receptor, KIAA0585
Concentration :
0.5mg/ml (determined by Bradford assay)
Formulation :
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 30% glycerol, 1mM DTT
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Hong X. et al. (2010) Proc. Natl. Acad. Sci. u.S.A. 107:14568-14572.;; Webby C.J. et al. (2009) Science 325:90-93.
Purity :
> 90% by SDS-PAGE
Applications :
SDS-PAGE
Antigen Species :
Human
Gene Category :
Apoptosis
Molecular Weight :
50kDa (437aa)
Amino Acid Sequence :
MNHKSKK RIREAKRSAR PELKDSLDWT RHNYYESFSL SPAAVADNVE RADALQLSVE EFVERYERPY KPVVLLNAQE GWSAQEKWTL ERLKRKYRNQ KFKCGEDNDG YSVKMKMKYY IEYMESTRDD SPLYIFDSSY GEHPKRRKLL EDYKVPKFFT DDLFQYAGEK RRPPYRWFVM GPPRSGTGIH IDPLGTSAWN ALVQGHKRWC LFPTSTPREL IKVTRDEGGN QQDEAITWFN VIYPRTQLPT WPPEFKPLEI LQKPGETVFV PGGWWHVVLN LDTTIAITQN FASSTNFPVV WHKTVRGRPK LSRKWYRILK QEHPELAVLA DSVDLQESTG IASDSSSDSS SSSSSSSSDS DSECESGSEG DGTVHRRKKR RTCSMVGNGD TTSQDDCVSK ERSSSRIRDT CGGRAHP
Tag :
His-Tag
Expression System :
E.coli
Product Type Name :
Recombinant Protein
UniProt No. :
Q6NYC1
Internal Search Terms :
Jumonji domain containing 6, Arginine demethylase and lysine hydroxylase, Phosphatidylserine receptor, KIAA0585, Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 isoform1, PSR, PTDSR, PTDSR1, JMJD6, PTDSR 1, JMJD 6, Bifunctional arginine demethylase and lysyl hydroxylase JMJD6 isoform1, ATGP2999-10ug, ATGP2999-20ug, ATGP2999-50ug, ATGP2999-100ug, ATGP2999-250ug, ATGP2999-500ug, ATGP2999-1mg, ATGP2999-010, ATGP2999-020, ATGP2999-050, ATGP2999-100, ATGP2999-250, ATGP2999-500, ATGP2999-01M
more info or order :
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.