Recombinant mouse IL-2 (C160S) protein | NKMAX ATGP2987 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant mouse IL-2 (C160S) protein

catalog :

ATGP2987

quantity :

10 ug

price :

105 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant mouse IL-2 (C160S) protein

Domain :

21-169aa

Catalog number (SKU) :

ATGP2987

NCBI :

NP_032392

Description :

IL2 (Interleukin2), also known as T cell growth factor (TCGF), is an immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. IL2/IL-2R signaling is required for T-cell proliferation and other fundamental functions which are essential for the immune response. IL2 stimulates growth and differentiation of B-cells, NK cells, lymphokine activated killer cells, monocytes, macrophages and oligodendrocytes. Recombinant mouse IL2 was expressed in E. coli and purified by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer.

Alternative Names :

Interleukin-2, IL-2, T-cell growth factor, TCGF

Concentration :

0.5mg/ml (determined by BCA assay)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4) 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Watson J., et al. (1980). Immunol Rev. 51:257-278.;; Taniguchi T., et al. (1983). Nature. 302: 305-310.

Purity :

> 90% by SDS-PAGE

Bioactivity Comment Only :

Measured in a cell proliferation assay using CTLL-2 mouse cytotoxic T cells. The ED50 range ≤0.9ng/ml.

Applications :

SDS-PAGE, Bioactivity

Antigen Species :

Mouse

Gene Category :

Hormones & Cytokines

Additional Comment Only :

ILB0905 has been replaced with a catalog number ATGP2987.

Molecular Weight :

17.3 kDa (150aa) confirmed by MALDI-TOF

Endotoxin :

< 1 EU per 1ug of protein (determined by LAL method)

Bioactivity Comment and Pics :

Mouse IL-2 (C160S) stimulates cell proliferation of the CTLL2 mouse cytotoxic T cells. The ED50 range ≤0.9 ng/ml.

Amino Acid Sequence :

MAPTSSSTSS STAEAQQQQQ QQQQQQQHLE QLLMDLQELL SRMENYRNLK LPRMLTFKFY LPKQATELKD LQCLEDELGP LRHVLDLTQS KSFQLEDAEN FISNIRVTVV KLKGSDNTFE CQFDDESATV VDFLRRWIAF SQSIISTSPQ

Tag :

Non-Tagged

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

P04351

Internal Search Terms :

ILB0905, C160S, IL 2, IL2, IL-2, Interleukin 2, Interleukin2, Interleukin-2, T cell growth factor, Tcell growth factor, T-cell growth factor, TCGF, ATGP2987-10ug, ATGP2987-20ug, ATGP2987-50ug, ATGP2987-100ug, ATGP2987-250ug, ATGP2987-500ug, ATGP2987-1mg, ATGP2987-010, ATGP2987-020, ATGP2987-050, ATGP2987-100, ATGP2987-250, ATGP2987-500, ATGP2987-01M

References with this Product :

Hyung KE, et al. Lactobacillus plantarum isolated from kimchi regulates inflammation by increasing interleukin-10 secretion by antigen-presenting cells, leading to diminishing of STAT5 phosphorylation in Th2 cells. (J Food Sci. 2024){https://pubmed.ncbi.nlm.nih.gov/38685880/}

more info or order :

NKMAX product webpage