Recombinant human IMPAD1 protein | NKMAX ATGP2986 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human IMPAD1 protein

catalog :

ATGP2986

quantity :

10 ug

price :

240 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human IMPAD1 protein

Domain :

34-359aa

Catalog number (SKU) :

ATGP2986

NCBI :

NP_060283

Description :

IMPAD1, also known as Inositol monophosphatase 3, is a member of the inositol monophosphatase family. IMPAD1 is localized to the Golgi apparatus and catalyzes the hydrolysis of phosphoadenosine phosphate (PAP) to adenosine monophosphate (AMP). Mutations in this gene are a cause of GRAPP type chondrodysplasia with joint dislocations, and a pseudogene of this gene is located on the long arm of chromosome 1. Recombinant human IMPAD1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer.

Alternative Names :

Inositol monophosphatase 3, GPAPP, IMP 3, IMP-3, IMPA3

Concentration :

0.25mg/ml (determined by Bradford assay)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4)

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Vissers L E., et al. (2011) Am J Hum Genet. 88:608-615. ;; Kalujnaia S., et al. (2010) FASEB J. 24:3981-3991.

Purity :

> 90% by SDS-PAGE

Bioactivity Comment Only :

Specific acitivty > 3300pmol/min/ug, its ability to dephosphorylate adenosine 3'5'-diphosphate sodium slat at pH 7.5, 25C.

Applications :

Enzyme Activity,SDS-PAGE

Antigen Species :

Human

Gene Category :

Cardiovascular

Molecular Weight :

37.6 kDa (349aa) confirmed by MALDI-TOF

Bioactivity Comment and Pics :

Specific acitivty > 3300 pmol/min/ug, its ability to dephosphorylate adenosine 3'5'-diphosphate sodium slat at pH 7.5, 25C.

Amino Acid Sequence :

MGSSHHHHHH SSGLVPRGSH MGSGRFSLFG LGGEPGGGAA GPAAAADGGT VDLREMLAVS VLAAVRGGDE VRRVRESNVL HEKSKGKTRE GAEDKMTSGD VLSNRKMFYL LKTAFPSVQI NTEEHVDAAD QEVILWDHKI PEDILKEVTT PKEVPAESVT VWIDPLDATQ EYTEDLRKYV TTMVCVAVNG KPMLGVIHKP FSEYTAWAMV DGGSNVKARS SYNEKTPRIV VSRSHSGMVK QVALQTFGNQ TTIIPAGGAG YKVLALLDVP DKSQEKADLY IHVTYIKKWD ICAGNAILKA LGGHMTTLSG EEISYTGSDG IEGGLLASIR MNHQALVRKL PDLEKTGHK

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

Q9NX62

Internal Search Terms :

IMPAD1, Inositol monophosphatase 3, GPAPP, IMP 3, IMP-3, IMPA3,ATGP2986-10ug,ATGP2986-20ug,ATGP2986-50ug,ATGP2986-100ug,ATGP2986-250ug,ATGP2986-500ug,ATGP2986-1mg,ATGP2986-10,ATGP2986-20,ATGP2986-50,ATGP2986-100,ATGP2986-250,ATGP2986-500,ATGP2986-1

more info or order :

NKMAX product webpage