Recombinant human Granzyme B protein | NKMAX ATGP2978 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human Granzyme B protein

catalog :

ATGP2978

quantity :

20 ug

price :

80 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human Granzyme B protein

Domain :

21-247aa

Catalog number (SKU) :

ATGP2978

NCBI :

NP_004122

Description :

GZMB also known as granzyme B is crucial for the rapid induction of target cell apoptosis by CTL in cell-mediated immune response. Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface nonself antigens, usually peptides or proteins resulting from infection by intracellular pathogens. Recombinant human GZMB, fused to His-tag at N-terminus, was expressed in E. coli.

Alternative Names :

Granzyme B, CCPI, CGL-1, CGL1, CSP-B, CSPB, CTLA1, CTSGL1, HLP, SECT

Concentration :

1mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Xu W., et al. (2014) Eur. J. Immunol. 44 (1), 275-284;; Fritsch K., et al. (2013) Ann. Hematol. 92 (12), 1603-1609

Purity :

> 85% by SDS-PAGE

Applications :

SDS-PAGE,Denatured

Antigen Species :

Human

Gene Category :

Apoptosis

Molecular Weight :

27.8 kDa (248aa)

Amino Acid Sequence :

MGSSHHHHHH SSGLVPRGSH MIIGGHEAKP HSRPYMAYLM IWDQKSLKRC GGFLIQDDFV LTAAHCWGSS INVTLGAHNI KEQEPTQQFI PVKRPIPHPA YNPKNFSNDI MLLQLERKAK RTRAVQPLRL PSNKAQVKPG QTCSVAGWGQ TAPLGKHSHT LQEVKMTVQE DRKCESDLRH YYDSTIELCV GDPEIKKTSF KGDSGGPLVC NKVAQGIVSY GRNNGMPPRA CTKVSSFVHW IKKTMKRY

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

P10144

Internal Search Terms :

Granzyme B, Granzyme B, CCPI, CGL-1, CGL1, CSP-B, CSPB, CTLA1, CTSGL1, HLP, SECT,ATGP2978-10ug,ATGP2978-20ug,ATGP2978-50ug,ATGP2978-100ug,ATGP2978-250ug,ATGP2978-500ug,ATGP2978-1mg,ATGP2978-10,ATGP2978-20,ATGP2978-50,ATGP2978-100,ATGP2978-250,ATGP2978-500,ATGP2978-1

more info or order :

NKMAX product webpage