product summary
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company name :
NKMAX
product type :
protein
product name :
Recombinant human PU.1/SPI1 protein
catalog :
ATGP2969
quantity :
10 ug
price :
80 USD
more info or order :
product information
Product Type :
Proteins
Item Name :
Recombinant human PU.1/SPI1 protein
Domain :
1-271aa
Catalog number (SKU) :
ATGP2969
NCBI :
NP_001074016
Description :
SPI1 also known as transcription factor Pu. 1, is a protein that in humans is encoded by the SPI1 gene. This protein have ETS-domain transcription factor that activates gene expression during myeloid and B-lymphoid cell development. The nuclear protein binds to a purine-rich sequence known as the Pu-box found near the promoters of target genes, and regulates their expression in coordination with other transcription factors and cofactors. It can also regulate alternative splicing of target genes. Multiple transcript variants encoding different isoforms have been found for this gene. Recombinant SPI1, fused to His-tag at N-terminus, was expressed in E. coli.
Alternative Names :
Transcription factor Pu.1 isoform 1, OF, Pu.1, SFPI1, SPI-1, SPI-A, Spi-1 proto-oncogene
Concentration :
0.25mg/ml (determined by Bradford assay)
Formulation :
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Ray D, Culine S, et al. (1990). Oncogene. 5(5):663-8.;; Hallier M, Tavitian A, et al. (1996). J Biol Chem. 271(19):11177-81.
Purity :
> 85% by SDS-PAGE
Applications :
SDS-PAGE, Denatured
Antigen Species :
Human
Gene Category :
Immunology
Molecular Weight :
33.6 kDa (294aa)
Amino Acid Sequence :
MGSSHHHHHH SSGLVPRGSH MGSMLQACKM EGFPLVPPQP SEDLVPYDTD LYQRQTHEYY PYLSSDGESH SDHYWDFHPH HVHSEFESFA ENNFTELQSV QPPQLQQLYR HMELEQMHVL DTPMVPPHPS LGHQVSYLPR MCLQYPSLSP AQPSSDEEEG ERQSPPLEVS DGEADGLEPG PGLLPGETGS KKKIRLYQFL LDLLRSGDMK DSIWWVDKDK GTFQFSSKHK EALAHRWGIQ KGNRKKMTYQ KMARALRNYG KTGEVKKVKK KLTYQFSGEV LGRGGLAERR HPPH
Tag :
His-Tag
Expression System :
E.coli
Product Type Name :
Recombinant Protein
UniProt No. :
P17947
Internal Search Terms :
SPI1, Transcription factor Pu.1 isoform 1, OF, Pu.1, SFPI1, SPI-1, SPI-A,ATGP2969-10ug,ATGP2969-20ug,ATGP2969-50ug,ATGP2969-100ug,ATGP2969-250ug,ATGP2969-500ug,ATGP2969-1mg,ATGP2969-10,ATGP2969-20,ATGP2969-50,ATGP2969-100,ATGP2969-250,ATGP2969-500,ATGP2969-1
more info or order :
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.