product summary
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company name :
NKMAX
product type :
protein
product name :
Recombinant human TSLP protein
catalog :
ATGP2950
quantity :
4 ug
price :
80 USD
more info or order :
product information
Product Type :
Proteins
Item Name :
Recombinant human TSLP protein
Domain :
29-159aa
Catalog number (SKU) :
ATGP2950
NCBI :
NP_149024
Description :
TSLP is a hemopoietic cytokine proposed to signal through a heterodimeric receptor complex composed of the thymic stromal lymphopoietin receptor and the IL-7R alpha chain. It mainly impacts myeloid cells and induces the release of T cell-attracting chemokines from monocytes and enhances the maturation of CD11c (+) dendritic cells. The protein promotes T helper type 2 (TH2) cell responses that are associated with immunity in various inflammatory diseases, including asthma, allergic inflammation and chronic obstructive pulmonary disease. TSLP is therefore considered a potential therapeutic target for the treatment of such diseases. Alternative splicing of this gene results in multiple transcript variants. Recombinant human TSLP protein, fused to His-tag at N-terminus, was expressed in E. coli.
Alternative Names :
Thymic stromal lymphopoietin
Concentration :
0.25mg/ml (determined by Bradford assay)
Formulation :
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Datta A.,et al. (2013) J. Immunol. 191 (9), 4867-4879
Purity :
> 85% by SDS-PAGE
Applications :
SDS-PAGE, Denatured
Antigen Species :
Human
Gene Category :
Immunology
Molecular Weight :
17.3 kDa (154aa)
Amino Acid Sequence :
YDFTNCD FEKIKAAYLS TISKDLITYM SGTKSTEFNN TVSCSNRPHC LTEIQSLTFN PTAGCASLAK EMFAMKTKAA LAIWCPGYSE TQINATQAMK KRRKRKVTTN KCLEQVSQLQ GLWRRFNRPL LKQQ
Tag :
His-Tag
Expression System :
E.coli
Product Type Name :
Recombinant Protein
UniProt No. :
Q969D9
Internal Search Terms :
TSLP, Thymic stromal lymphopoietin,ATGP2950-10ug,ATGP2950-20ug,ATGP2950-50ug,ATGP2950-100ug,ATGP2950-250ug,ATGP2950-500ug,ATGP2950-1mg,ATGP2950-10,ATGP2950-20,ATGP2950-50,ATGP2950-100,ATGP2950-250,ATGP2950-500,ATGP2950-1
more info or order :
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.