Recombinant human NRF2/NFE2L2 protein | NKMAX ATGP2948 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human NRF2/NFE2L2 protein

catalog :

ATGP2948

quantity :

4 ug

price :

80 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human NRF2/NFE2L2 protein

Domain :

1-605aa

Catalog number (SKU) :

ATGP2948

NCBI :

NP_006155.2

Description :

Nuclear factor (erythroid-derived 2) -like 2, also known as NRF2, is bZIP transcription factors that heterodimerize with Maf proteins to bind Mare sequences. The NRF proteins also bind the antioxidant response element (ARE) and are implicated in the regulation of detoxification enzymes and the oxidative stress response. NRF2 is widely expressed and is thought to translocate to the nucleus after treatment with xenobiotics and antioxidants, which stimulate its release from its repressor protein, Keap1. Recombinant human NRF2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Alternative Names :

NFE2 like bZIP transcription factor 2, Nuclear factor erythroid 2-related factor 2, NRF-2, NF-E2-related factor 2, HEBP1

Concentration :

0.25mg/ml (determined by Bradford assay)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Huang H C., et al. (2000) Proc Natl Acad Sci uSA. 97: 12475-12480.;; Tsai P Y., et al. (2012) Arthritis Rheum. 64: 232-242.;;

Purity :

> 85% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Epigenetics and Nuclear Signaling

Molecular Weight :

69.9 kDa (625aa)

Amino Acid Sequence :

MMDLELPPPG LPSQQDMDLI DILWRQDIDL GVSREVFDFS QRRKEYELEK QKKLEKERQE QLQKEQEKAF FAQLQLDEET GEFLPIQPAQ HIQSETSGSA NYSQVAHIPK SDALYFDDCM QLLAQTFPFV DDNEVSSATF QSLVPDIPGH IESPVFIATN QAQSPETSVA QVAPVDLDGM QQDIEQVWEE LLSIPELQCL NIENDKLVET TMVPSPEAKL TEVDNYHFYS SIPSMEKEVG NCSPHFLNAF EDSFSSILST EDPNQLTVNS LNSDATVNTD FGDEFYSAFI AEPSISNSMP SPATLSHSLS ELLNGPIDVS DLSLCKAFNQ NHPESTAEFN DSDSGISLNT SPSVASPEHS VESSSYGDTL LGLSDSEVEE LDSAPGSVKQ NGPKTPVHSS GDMVQPLSPS QGQSTHVHDA QCENTPEKEL PVSPGHRKTP FTKDKHSSRL EAHLTRDELR AKALHIPFPV EKIINLPVVD FNEMMSKEQF NEAQLALIRD IRRRGKNKVA AQNCRKRKLE NIVELEQDLD HLKDEKEKLL KEKGENDKSL HLLKKQLSTL YLEVFSMLRD EDGKPYSPSE YSLQQTRDGN VFLVPKSKKP DVKKN

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

Q16236

Internal Search Terms :

NRF2,ATGP2948-10ug,ATGP2948-20ug,ATGP2948-50ug,ATGP2948-100ug,ATGP2948-250ug,ATGP2948-500ug,ATGP2948-1mg,ATGP2948-10,ATGP2948-20,ATGP2948-50,ATGP2948-100,ATGP2948-250,ATGP2948-500,ATGP2948-1

more info or order :

NKMAX product webpage