product summary
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company name :
NKMAX
product type :
protein
product name :
Recombinant human IL-12R beta/IL12RB1 protein
catalog :
ATGP2945
quantity :
10 ug
price :
105 USD
more info or order :
product information
Product Type :
Proteins
Item Name :
Recombinant human IL-12R beta/IL12RB1 protein
Domain :
1-545aa
Catalog number (SKU) :
ATGP2945
NCBI :
NP_005526
Description :
IL12RB1 is a type I transmembrane protein that belongs to the hemopoietin receptor superfamily. This protein binds to interleukine 12 (IL12) with a low affinity, and is thought to be a part of IL12 receptor complex. This protein forms a disulfide-linked oligomer, which is required for its IL12 binding activity. The coexpression of this and IL12RB2 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. Recombinant human IL12RB1 protein, fused to His-tag at N-terminus, was expressed in E. coli.
Alternative Names :
Interleukin 12 receptor subunit beta 1, IL-12 receptor subunit beta-1, IL-12R subunit beta-1, IL-12R-beta-1, IL-12 receptor beta component, IL12R, IL12RB, CD212
Concentration :
0.25mg/ml (determined by Bradford assay)
Formulation :
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Li X., et al. (2013) . Allergy Clin. Immunol. 132 (2), 313-320;; Giatrakos S, et al. (2013) Cytokine 62 (2), 297-301;;
Purity :
> 90% by SDS-PAGE
Applications :
SDS-PAGE, Denatured
Antigen Species :
Human
Gene Category :
Immunology
Molecular Weight :
62.6 kDa (568aa)
Amino Acid Sequence :
MGSSHHHHHH SSGLVPRGSH MGSMEPLVTW VVPLLFLFLL SRQGAACRTS ECCFQDPPYP DADSGSASGP RDLRCYRISS DRYECSWQYE GPTAGVSHFL RCCLSSGRCC YFAAGSATRL QFSDQAGVSV LYTVTLWVES WARNQTEKSP EVTLQLYNSV KYEPPLGDIK VSKLAGQLRM EWETPDNQVG AEVQFRHRTP SSPWKLGDCG PQDDDTESCL CPLEMNVAQE FQLRRRQLGS QGSSWSKWSS PVCVPPENPP QPQVRFSVEQ LGQDGRRRLT LKEQPTQLEL PEGCQGLAPG TEVTYRLQLH MLSCPCKAKA TRTLHLGKMP YLSGAAYNVA VISSNQFGPG LNQTWHIPAD THTEPVALNI SVGTNGTTMY WPARAQSMTY CIEWQPVGQD GGLATCSLTA PQDPDPAGMA TYSWSRESGA MGQEKCYYIT IFASAHPEKL TLWSTVLSTY HFGGNASAAG TPHHVSVKNH SLDSVSVDWA PSLLSTCPGV LKEYVVRCRD EDSKQVSEHP VQPTETQVTL SGLRAGVAYT VQVRADTAWL RGVWSQPQRF SIEVQVSD
Tag :
His-Tag
Expression System :
E.coli
Product Type Name :
Recombinant Protein
UniProt No. :
P42701
Internal Search Terms :
IL12 R b1, Interleukin-12 receptor subunit beta-1, Interleukin-12 receptor subunit beta-1, CD212, IL-12R-BETA1, IL12RB,ATGP2945-10ug,ATGP2945-20ug,ATGP2945-50ug,ATGP2945-100ug,ATGP2945-250ug,ATGP2945-500ug,ATGP2945-1mg,ATGP2945-10,ATGP2945-20,ATGP2945-50,ATGP2945-100,ATGP2945-250,ATGP2945-500,ATGP2945-1
more info or order :
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.