product summary
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company name :
NKMAX
product type :
protein
product name :
Recombinant human THOC7 protein
catalog :
ATGP2943
quantity :
10 ug
price :
105 USD
more info or order :
product information
Product Type :
Proteins
Item Name :
Recombinant human THOC7 protein
Domain :
1-204aa
Catalog number (SKU) :
ATGP2943
NCBI :
NP_079351
Description :
THOC7 is required for efficient export of polyadenylated RNA. This protein acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway. The TREX complex is essential for the export of Kaposi's sarcoma-associated herpesvirus (KSHV) intronless mRNAs and infectious virus production. Recombinant human THOC7 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Alternative Names :
THO complex subunit 7 homolog, fSAP24, hTREX30, NIF3L1BP1
Concentration :
0.5mg/ml (determined by Bradford assay)
Formulation :
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing, 50% glycerol, 1mM DTT
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
El Bounkari O., et al. (2009) FEBS Lett. 583 (1), 13-18
Purity :
> 90% by SDS-PAGE
Applications :
SDS-PAGE
Antigen Species :
Human
Gene Category :
Epigenetics and Nuclear Signaling
Molecular Weight :
26.1 kDa (227aa) confirmed by MALDI-TOF
Amino Acid Sequence :
MGAVTDD EVIRKRLLID GDGAGDDRRI NLLVKSFIKW CNSGSQEEGY SQYQRMLSTL SQCEFSMGKT LLVYDMNLRE MENYEKIYKE IECSIAGAHE KIAECKKQIL QAKRIRKNRQ EYDALAKVIQ HHPDRHETLK ELEALGKELE HLSHIKESVE DKLELRRKQF HVLLSTIHEL QQTLENDEKL SEVEEAQEAS METDPKP
Tag :
His-Tag
Expression System :
E.coli
Product Type Name :
Recombinant Protein
UniProt No. :
Q6I9Y2
Internal Search Terms :
THOC7, THO complex subunit 7 homolog, fSAP24, hTREX30, NIF3L1BP1,ATGP2943-10ug,ATGP2943-20ug,ATGP2943-50ug,ATGP2943-100ug,ATGP2943-250ug,ATGP2943-500ug,ATGP2943-1mg,ATGP2943-10,ATGP2943-20,ATGP2943-50,ATGP2943-100,ATGP2943-250,ATGP2943-500,ATGP2943-1
more info or order :
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.