Recombinant human ZFAND5 protein | NKMAX ATGP2931 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human ZFAND5 protein

catalog :

ATGP2931

quantity :

20 ug

price :

80 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human ZFAND5 protein

Domain :

1-213aa

Catalog number (SKU) :

ATGP2931

NCBI :

NP_005998

Description :

ZFAND5 is involved in protein degradation via the ubiquitin-proteasome system. This protein may act by anchoring ubiquitinated proteins to the proteasome and plays a role in ubiquitin-mediated protein degradation during muscle atrophy. ZFAND5 plays a role in the regulation of NF-kappa-B activation and apoptosis and inhibits NF-kappa-B activation triggered by overexpression of RIPK1 and TRAF6 but not of RELA. It inhibits also tumor necrosis factor (TNF), IL-1 and TLR4-induced NF-kappa-B activation in a dose-dependent manner. Recombinant human ZFAND5 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Alternative Names :

AN1-type zinc finger protein 5, AN1-type zinc finger protein 5, ZA20D2, ZFAND5A, ZNF216

Concentration :

0.5mg/ml (determined by Bradford assay)

Formulation :

Liquid In. Phosphate-Buffered Saline (pH 7.4) containing 30% glycerol, 1mM DTT

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Huang J., et al. (2004) J. Biol. Chem. 279:16847-16853.;; Gauci S., et al. (2009) Anal. Chem. 81:4493-4501.;;

Purity :

> 85% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Apoptosis

Molecular Weight :

25.5 kDa (236aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)

Amino Acid Sequence :

MGSSHHHHHH SSGLVPRGSH MGSMAQETNQ TPGPMLCSTG CGFYGNPRTN GMCSVCYKEH LQRQQNSGRM SPMGTASGSN SPTSDSASVQ RADTSLNNCE GAAGSTSEKS RNVPVAALPV TQQMTEMSIS REDKITTPKT EVSEPVVTQP SPSVSQPSTS QSEEKAPELP KPKKNRCFMC RKKVGLTGFD CRCGNLFCGL HRYSDKHNCP YDYKAEAAAK IRKENPVVVA EKIQRI

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

O76080

Internal Search Terms :

ZFAND5, AN1-type zinc finger protein 5, AN1-type zinc finger protein 5, ZA20D2, ZFAND5A, ZNF216,ATGP2931-10ug,ATGP2931-20ug,ATGP2931-50ug,ATGP2931-100ug,ATGP2931-250ug,ATGP2931-500ug,ATGP2931-1mg,ATGP2931-10,ATGP2931-20,ATGP2931-50,ATGP2931-100,ATGP2931-250,ATGP2931-500,ATGP2931-1

more info or order :

NKMAX product webpage