Recombinant human Akt1 protein | NKMAX ATGP2915 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human Akt1 protein

catalog :

ATGP2915

quantity :

20 ug

price :

80 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human Akt1 protein

Domain :

1-480aa

Catalog number (SKU) :

ATGP2915

NCBI :

NP_001014432

Description :

AKT1 serine-threonine protein kinase is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3-kinase. In the developing nervous system AKT is a critical mediator of growth factor-induced neuronal survival. Recombinant human AKT1 protein, fused to His-tag at N-terminus, was expressed in E. coli.

Alternative Names :

Protein kinase B, Protein kinase B alpha, Proto-oncogene c-Akt, RAC-PK-alpha

Concentration :

0.5mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Dobashi Y., et al. (2014) Hum. Pathol. 45 (1), 127-136;; Liu K, et al. (2013) Mol. Cell. Biol. 33 (23), 4685-4700;;

Purity :

> 85% by SDS-PAGE

Applications :

SDS-PAGE, Denatured

Antigen Species :

Human

Gene Category :

Signal Transduction

Molecular Weight :

58.1 kDa (503aa)

Amino Acid Sequence :

MGSSHHHHHH SSGLVPRGSH MGSMSDVAIV KEGWLHKRGE YIKTWRPRYF LLKNDGTFIG YKERPQDVDQ REAPLNNFSV AQCQLMKTER PRPNTFIIRC LQWTTVIERT FHVETPEERE EWTTAIQTVA DGLKKQEEEE MDFRSGSPSD NSGAEEMEVS LAKPKHRVTM NEFEYLKLLG KGTFGKVILV KEKATGRYYA MKILKKEVIV AKDEVAHTLT ENRVLQNSRH PFLTALKYSF QTHDRLCFVM EYANGGELFF HLSRERVFSE DRARFYGAEI VSALDYLHSE KNVVYRDLKL ENLMLDKDGH IKITDFGLCK EGIKDGATMK TFCGTPEYLA PEVLEDNDYG RAVDWWGLGV VMYEMMCGRL PFYNQDHEKL FELILMEEIR FPRTLGPEAK SLLSGLLKKD PKQRLGGGSE DAKEIMQHRF FAGIVWQHVY EKKLSPPFKP QVTSETDTRY FDEEFTAQMI TITPPDQDDS MECVDSERRP HFPQFSYSAS GTA

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

P31749

Internal Search Terms :

Akt1, RAC-alpha serine/threonine-protein kinase, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA,ATGP2915-10ug,ATGP2915-20ug,ATGP2915-50ug,ATGP2915-100ug,ATGP2915-250ug,ATGP2915-500ug,ATGP2915-1mg,ATGP2915-10,ATGP2915-20,ATGP2915-50,ATGP2915-100,ATGP2915-250,ATGP2915-500,ATGP2915-1

more info or order :

NKMAX product webpage