Recombinant human TNFR1/TNFRSF1A protein | NKMAX ATGP2883 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human TNFR1/TNFRSF1A protein

catalog :

ATGP2883

quantity :

20 ug

price :

80 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human TNFR1/TNFRSF1A protein

Domain :

22-211aa

Catalog number (SKU) :

ATGP2883

NCBI :

NP_001056

Description :

TNFRSF1A is a member of the TNF-receptor superfamily. This protein is one of the major receptors for the tumor necrosis factor-alpha. This receptor can activate NF-kappaB, mediate apoptosis, and function as a regulator of inflammation. Antiapoptotic protein BCL2-associated athanogene 4 (BAG4/SODD) and adaptor proteins TRADD and TRAF2 have been shown to interact with this receptor, and thus play regulatory roles in the signal transduction mediated by the receptor. Germline mutations of the extracellular domains of this receptor were found to be associated with the autosomal dominant periodic fever syndrome. The impaired receptor clearance is thought to be a mechanism of the disease. Recombinant human TNFRSF1A protein, fused to His-tag at N-terminus, was expressed in E. coli.

Alternative Names :

Tumor necrosis factor receptor superfamily member 1A, Tumor necrosis factor receptor 1, TNF-R1, Tumor necrosis factor receptor type I, TNF-RI, TNFR-I, Tumor necrosis factor-binding protein 1, TBPI, CS120a, p55, p60, TNF-R55, TNFR60

Concentration :

1mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Loetscher H., et al. (1990) Cell, 61:351-359

Purity :

> 85% by SDS-PAGE

Applications :

SDS-PAGE, Denatured

Antigen Species :

Human

Gene Category :

Apoptosis

Molecular Weight :

23.6 kDa (213aa)

Amino Acid Sequence :

MGSSHHHHHH SSGLVPRGSH MGSIYPSGVI GLVPHLGDRE KRDSVCPQGK YIHPQNNSIC CTKCHKGTYL YNDCPGPGQD TDCRECESGS FTASENHLRH CLSCSKCRKE MGQVEISSCT VDRDTVCGCR KNQYRHYWSE NLFQCFNCSL CLNGTVHLSC QEKQNTVCTC HAGFFLRENE CVSCSNCKKS LECTKLCLPQ IENVKGTEDS GTT

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

P19438

Internal Search Terms :

sTNF RI, TNFRSF1A, Tumor necrosis factor receptor superfamily member 1A, Tumor necrosis factor receptor superfamily member 1A, CD120a, FPF, MS5, p55, p55-R, p60, TBP1, TNF-R, TNF-R-I, TNF-R55, TNFAR, TNFR1, TNFR1-d2, TNFR55, TNFR60,ATGP2883-10ug,ATGP2883-20ug,ATGP2883-50ug,ATGP2883-100ug,ATGP2883-250ug,ATGP2883-500ug,ATGP2883-1mg,ATGP2883-10,ATGP2883-20,ATGP2883-50,ATGP2883-100,ATGP2883-250,ATGP2883-500,ATGP2883-1

more info or order :

NKMAX product webpage