Recombinant human CDK2 protein | NKMAX ATGP2878 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human CDK2 protein

catalog :

ATGP2878

quantity :

20 ug

price :

80 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human CDK2 protein

Domain :

1-298aa

Catalog number (SKU) :

ATGP2878

NCBI :

NP_001789.2

Description :

Cyclin-dependent kinase 2, also known as CDK2, phosphorylates CTNNB1, uSP37, p53/TP53, NPM1, CDK7, RB1, BRCA2, MYC, NPAT, EZH2. This protein acts at the G1-S transition to promote the E2F transcriptional program and the initiation of DNA synthesis, and modulates G2 progression; controls the timing of entry into mitosis/meiosis by controlling the subsequent activation of cyclin B/CDK1 by phosphorylation, and coordinates the activation of cyclin B/CDK1 at the centrosome and in the nucleus. This protein is crucial role in orchestrating a fine balance between cellular proliferation, cell death, and DNA repair in human embryonic stem cells (hESCs). Recombinant human CDK2 protein, fused to His-tag at C-terminus, was expressed in insect cells using baculovirus expression system and purified by using conventional chromatography techniques.

Alternative Names :

Cyclin-dependent kinase 2, p33 (CDK2)

Concentration :

0.5mg/ml (determined by Bradford assay)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4) 30% glycerol, 2mM DTT, 0.1mM PMSF

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Okuda M., et al. (2000) Cell. 103:127-140.;; Ma T., et al. (2000) Genes Dev. 14:2298-2313.;;

Purity :

> 90% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Cell Cycle

Molecular Weight :

34.9 kDa (306aa)

Amino Acid Sequence :

MENFQKVEKI GEGTYGVVYK ARNKLTGEVV ALKKIRLDTE TEGVPSTAIR EISLLKELNH PNIVKLLDVI HTENKLYLVF EFLHQDLKKF MDASALTGIP LPLIKSYLFQ LLQGLAFCHS HRVLHRDLKP QNLLINTEGA IKLADFGLAR AFGVPVRTYT HEVVTLWYRA PEILLGCKYY STAVDIWSLG CIFAEMVTRR ALFPGDSEID QLFRIFRTLG TPDEVVWPGV TSMPDYKPSF PKWARQDFSK VVPPLDEDGR SLLSQMLHYD PNKRISAKAA LAHPFFQDVT KPVPHLRL

Tag :

His-Tag

Expression System :

Baculovirus

Product Type Name :

Recombinant Protein

UniProt No. :

P24941

Internal Search Terms :

CDK2, Cyclin-dependent kinase 2, p33 (CDK2),ATGP2878-10ug,ATGP2878-20ug,ATGP2878-50ug,ATGP2878-100ug,ATGP2878-250ug,ATGP2878-500ug,ATGP2878-1mg,ATGP2878-10,ATGP2878-20,ATGP2878-50,ATGP2878-100,ATGP2878-250,ATGP2878-500,ATGP2878-1

more info or order :

NKMAX product webpage