Recombinant human BRD2 protein | NKMAX ATGP2876 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human BRD2 protein

catalog :

ATGP2876

quantity :

20 ug

price :

80 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human BRD2 protein

Domain :

1-455aa

Catalog number (SKU) :

ATGP2876

NCBI :

NP_005095

Description :

BRD2 is a transcriptional regulator that belongs to the BET (bromodomains and extra terminal domain) family of roteins. This protein associates with transcription complexes and ith acetylated chromatin during mitosis, and it selectively binds o the acetylated lysine-12 residue of histone H4 via its two romodomains. The gene maps to the major histocompatability complex MHC) class II region on chromosome 6p21. 3, but sequence comparison uggests that the protein is not involved in the immune response. This gene has been implicated in juvenile myoclonic epilepsy, a common form of epilepsy that becomes apparent in adolescence. Recombinant human BRD2 protein, fused to His-tag at N-terminus, was expressed in E. coli.

Alternative Names :

Bromodomain containing 2, D6S113E, FSH, FSRG1, NAT, RING3, RNF3

Concentration :

1mg/ml (determined by Bradford assay)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing, 10% glycerol, 1mM DTT

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Boehm,D., et al. (2013) Cell Cycle 12 (3), 452-462;; Tang,X., et al. (2013) Mol. Pharmacol. 83 (1), 283-293;;

Purity :

> 90% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Signal Transduction

Molecular Weight :

52.8 kDa (478aa)

Amino Acid Sequence :

MLQNVTP HNKLPGEGNA GLLGLGPEAA APGKRIRKPS LLYEGFESPT MASVPALQLT PANPPPPEVS NPKKPGRVTN QLQYLHKVVM KALWKHQFAW PFRQPVDAVK LGLPDYHKII KQPMDMGTIK RRLENNYYWA ASECMQDFNT MFTNCYIYNK PTDDIVLMAQ TLEKIFLQKV ASMPQEEQEL VVTIPKNSHK KGAKLAALQG SVTSAHQVPA VSSVSHTALY TPPPEIPTTV LNIPHPSVIS SPLLKSLHSA GPPLLAVTAA PPAQPLAKKK GVKRKADTTT PTPTAILAPG SPASPPGSLE PKAARLPPMR RESGRPIKPP RKDLPDSQQQ HQSSKKGKLS EQLKHCNGIL KELLSKKHAA YAWPFYKPVD ASALGLHDYH DIIKHPMDLS TVKRKMENRD YRDAQEFAAD VRLMFSNCYK YNPPDHDVVA MARKLQDVFE FRYAKMPD

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

P25440

Internal Search Terms :

BRD2, Bromodomain containing 2, D6S113E, FSH, FSRG1, NAT, RING3, RNF3,ATGP2876-10ug,ATGP2876-20ug,ATGP2876-50ug,ATGP2876-100ug,ATGP2876-250ug,ATGP2876-500ug,ATGP2876-1mg,ATGP2876-10,ATGP2876-20,ATGP2876-50,ATGP2876-100,ATGP2876-250,ATGP2876-500,ATGP2876-1

more info or order :

NKMAX product webpage