product summary
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company name :
NKMAX
product type :
protein
product name :
Recombinant human SMARCA4 protein
catalog :
ATGP2799
quantity :
20 ug
price :
80 USD
more info or order :
product information
Product Type :
Proteins
Item Name :
Recombinant human SMARCA4 protein
Domain :
362-549aa
Catalog number (SKU) :
ATGP2799
NCBI :
NP_001122321
Description :
SMARCA4 is a member of the SWI/SNF family of proteins and is similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. In addition, this protein can bind BRCA1, as well as regulate the expression of the tumorigenic protein CD44. Mutations in this gene cause rhabdoid tumor predisposition syndrome type 2. Multiple transcript variants encoding different isoforms have been found for this gene. Recombinant human SMARCA4 protein, fused to His-tag at N-terminus, was expressed in E. coli.
Alternative Names :
Transcription activator BRG1 isoform A, BAF190, BAF190A, BRG1, hSNF2b, MRD16, RTPS2, SNF2, SNF2L4, SNF2LB, SWI2
Concentration :
1mg/ml (determined by Bradford assay)
Formulation :
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Dykhuizen,E.C, et al. (2013) Nature 497 (7451), 624-627 ;; Bai,J., et al. (2013) PLoS ONE 8 (3), E59772
Purity :
> 80% by SDS-PAGE
Applications :
SDS-PAGE, Denatured
Antigen Species :
Human
Gene Category :
Neuroscience
Molecular Weight :
25kDa (211aa)
Amino Acid Sequence :
MGSSHHHHHH SSGLVPRGSH MGSDPVEILQ EREYRLQARI AHRIQELENL PGSLAGDLRT KATIELKALR LLNFQRQLRQ EVVVCMRRDT ALETALNAKA YKRSKRQSLR EARITEKLEK QQKIEQERKR RQKHQEYLNS ILQHAKDFKE YHRSVTGKIQ KLTKAVATYH ANTEREQKKE NERIEKERMR RLMAEDEEGY RKLIDQKKDK R
Tag :
His-Tag
Expression System :
E.coli
Product Type Name :
Recombinant Protein
UniProt No. :
Q9HBD4
Internal Search Terms :
SMARCA4, Transcription activator BRG1 isoform A, BAF190, BAF190A, BRG1, hSNF2b, MRD16, RTPS2, SNF2, SNF2L4, SNF2LB, SWI2,ATGP2799-10ug,ATGP2799-20ug,ATGP2799-50ug,ATGP2799-100ug,ATGP2799-250ug,ATGP2799-500ug,ATGP2799-1mg,ATGP2799-10,ATGP2799-20,ATGP2799-50,ATGP2799-100,ATGP2799-250,ATGP2799-500,ATGP2799-1
more info or order :
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.