product summary
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company name :
NKMAX
product type :
protein
product name :
Recombinant human LAMTOR4 protein
catalog :
ATGP2791
quantity :
4 ug
price :
80 USD
more info or order :
product information
Product Type :
Proteins
Item Name :
Recombinant human LAMTOR4 protein
Domain :
1-99aa
Catalog number (SKU) :
ATGP2791
NCBI :
NP_001008396
Description :
LAMTOR4 is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Activated by amino acids through a mechanism involving the lysosomal V-ATPase, the Ragulator functions as a guanine nucleotide exchange factor activating the small GTPases Rag. Activated Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated. Recombinant human LAMTOR4 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Alternative Names :
Ragulator complex protein LAMTOR4, C7orf59
Concentration :
0.25mg/ml (determined by Bradford assay)
Formulation :
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol, 1mM DTT
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Bar-Peled L., et al. (2011) Cell. 150:1196-1208;; Burkard T.R., et al. (2012) BMC Syst. Biol. 5:17-17
Purity :
> 85% by SDS-PAGE
Applications :
SDS-PAGE
Antigen Species :
Human
Gene Category :
Signal Transduction
Molecular Weight :
13.1 kDa (122aa) confirmed by MALDI-TOF
Amino Acid Sequence :
MGSSHHHHHH SSGLVPRGSH MGSMTSALTQ GLERIPDQLG YLVLSEGAVL ASSGDLENDE QAASAISELV STACGFRLHR GMNVPFKRLS VVFGEHTLLV TVSGQRVFVV KRQNRGREPI DV
Tag :
His-Tag
Expression System :
E.coli
Product Type Name :
Recombinant Protein
UniProt No. :
Q0VGL1
Internal Search Terms :
LAMTOR4, Ragulator complex protein LAMTOR4, C7orf59,ATGP2791-10ug,ATGP2791-20ug,ATGP2791-50ug,ATGP2791-100ug,ATGP2791-250ug,ATGP2791-500ug,ATGP2791-1mg,ATGP2791-10,ATGP2791-20,ATGP2791-50,ATGP2791-100,ATGP2791-250,ATGP2791-500,ATGP2791-1
more info or order :
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.