product summary
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company name :
NKMAX
product type :
protein
product name :
Recombinant human JTB protein
catalog :
ATGP2782
quantity :
4 ug
price :
80 USD
more info or order :
product information
Product Type :
Proteins
Item Name :
Recombinant human JTB protein
Domain :
31-105aa
Catalog number (SKU) :
ATGP2782
NCBI :
NP_006685
Description :
Jumping translocation breakpoint, also known as JTB, is required for normal cytokinesis during mitosis. This protein plays a role in the regulation of cell proliferation. This protein may be a component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. It lnhibits apoptosis induced by TGFB1. Overexpression induces swelling of mitochondria and reduces mitochondrial membrane potential. Recombinant human JTB protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Alternative Names :
Jumping translocation breakpoint, hJT, HJTB, HSPC222, PAR
Concentration :
0.25mg/ml (determined by Bradford assay)
Formulation :
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol, 1mM DTT
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Platica M., et al. (2011) Int. J. Oncol. 38:777-785;; Kanome T., et al. (2007) Oncogene. 26:5991-6001
Purity :
> 85% by SDS-PAGE
Applications :
SDS-PAGE
Antigen Species :
Human
Gene Category :
Other
Molecular Weight :
10.7 kDa (98aa) confirmed by MALDI-TOF
Amino Acid Sequence :
MGSSHHHHHH SSGLVPRGSH MGSEAPVQEE KLSASTSNLP CWLVEEFVVA EECSPCSNFR AKTTPECGPT GYVEKITCSS SKRNEFKSCR SALMEQRL
Tag :
His-Tag
Expression System :
E.coli
Product Type Name :
Recombinant Protein
UniProt No. :
O76095
Internal Search Terms :
JTB, Jumping translocation breakpoint, hJT, HJTB, HSPC222, PAR,ATGP2782-10ug,ATGP2782-20ug,ATGP2782-50ug,ATGP2782-100ug,ATGP2782-250ug,ATGP2782-500ug,ATGP2782-1mg,ATGP2782-10,ATGP2782-20,ATGP2782-50,ATGP2782-100,ATGP2782-250,ATGP2782-500,ATGP2782-1
more info or order :
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.