Recombinant human RNA polymerases I and III subunit RPAC1/POLR1C protein

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human RNA polymerases I and III subunit RPAC1/POLR1C protein

catalog :

ATGP2753

quantity :

10 ug

price :

105 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human RNA polymerases I and III subunit RPAC1/POLR1C protein

Domain :

1-349aa

Catalog number (SKU) :

ATGP2753

NCBI :

NP_976035

Description :

POLR1C is a subunit of both RNA polymerase I and RNA polymerase III complexes. The encoded protein is part of the Pol core element. Defects in this gene have been associated with Treacher Collins syndrome (TCS). Recombinant human POLR1C protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Alternative Names :

DNA-directed RNA polymerases I and III subunit RPAC1, RP3-337H4.4, RPA39, RPA40, RPA5, RPAC1, TCS3

Concentration :

0.5mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 20% glycerol, 1mM DTT

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Hu P., et al (2002). Mol. Cell. Biol. 22:8044-8055;; Dauwerse J.G., et al (2011). Nat. Genet. 43:20-22;;

Purity :

> 80% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Epigenomics (Transcription & Translation)

Molecular Weight :

41.6 kDa (369aa) confirmed by MALDI-TOF

Amino Acid Sequence :

MGSSHHHHHH SSGLVPRGSH MGSMAASQAV EEMRSRVVLG EFGVRNVHTT DFPGNYSGYD DAWDQDRFEK NFRVDVVHMD ENSLEFDMVG IDAAIANAFR RILLAEVPTM AVEKVLVYNN TSIVQDEILA HRLGLIPIHA DPRLFEYRNQ GDEEGTEIDT LQFRLQVRCT RNPHAAKDSS DPNELYVNHK VYTRHMTWIP LGNQADLFPE GTIRPVHDDI LIAQLRPGQE IDLLMHCVKG IGKDHAKFSP VATASYRLLP DITLLEPVEG EAAEELSRCF SPGVIEVQEV QGKKVARVAN PRLDTFSREI FRNEKLKKVV RLARVRDHYI FSVESTGVLP PDVLVSEAIK VLMGKCRRFL DELDAVQMD

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

O15160

Internal Search Terms :

POLR1C, DNA-directed RNA polymerases I and III subunit RPAC1, RP3-337H4.4, RPA39, RPA40, RPA5, RPAC1, TCS3,ATGP2753-10ug,ATGP2753-20ug,ATGP2753-50ug,ATGP2753-100ug,ATGP2753-250ug,ATGP2753-500ug,ATGP2753-1mg,ATGP2753-10,ATGP2753-20,ATGP2753-50,ATGP2753-100,ATGP2753-250,ATGP2753-500,ATGP2753-1

more info or order :

NKMAX product webpage