product summary
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company name :
NKMAX
product type :
protein
product name :
Recombinant HCV NS5a protein
catalog :
ATGP2739
quantity :
4 ug
price :
80 USD
more info or order :
NKMAX product webpage
product information
Product Type :
Proteins
Item Name :
Recombinant HCV NS5a protein
Domain :
2210-2306aa
Catalog number (SKU) :
ATGP2739
NCBI :
NP_671491
Description :
NS5A is a component of the replication complex involved in RNA-binding. Its interaction with Human VAPB may target the viral replication complex to vesicles. This protein down-regulates viral IRES translation initiation and mediates interferon resistance, presumably by interacting with and inhibiting human EIF2AK2/PKR. NS5a seems to inhibit apoptosis by interacting with BIN1 and FKBP8. The hyperphosphorylated form of NS5A is an inhibitor of viral replication. Recombinant HCV (Hepatitis C Virus) NS5A protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Alternative Names :
Polyprotein, Hepatitis C virus non-structural 5a protein membrane anchor
Concentration :
0.25mg/ml (determined by Bradford assay)
Formulation :
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 40% glycerol, 1mM DTT
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Taylor D.R., et al. (2001) J. Virol. 75:1265-1273;; Kalliampakou K.I., et al. (2015) J. Gen. Virol. 86:1015-1025
Purity :
> 90% by SDS-PAGE
Applications :
SDS-PAGE
Antigen Species :
HCV
Gene Category :
Virus
Molecular Weight :
13.4 kDa (118aa) confirmed by MALDI-TOF
Amino Acid Sequence :
MGSSHHHHHH SSGLVPRGSH MSLKATCTAN HDSPDAELIE ANLLWRQEMG GNITRVESENKVVILDSFDP LVAEEDEREV SVPAEILRKS RRFARALPVW ARPDYNPPLV ETWKKPDY
Tag :
His-Tag
Expression System :
E.coli
Product Type Name :
Recombinant Protein
Internal Search Terms :
HCV, HCV NS5a, Polyprotein, Hepatitis C virus non-structural 5a protein membrane anchor,ATGP2739-10ug,ATGP2739-20ug,ATGP2739-50ug,ATGP2739-100ug,ATGP2739-250ug,ATGP2739-500ug,ATGP2739-1mg,ATGP2739-10,ATGP2739-20,ATGP2739-50,ATGP2739-100,ATGP2739-250,ATGP2739-500,ATGP2739-1
more info or order :
NKMAX product webpage
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.