product summary
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company name :
NKMAX
product type :
protein
product name :
Recombinant human HGF protein
catalog :
ATGP2718
quantity :
20 ug
price :
80 USD
more info or order :
product information
Product Type :
Proteins
Item Name :
Recombinant human HGF protein
Domain :
32-285aa
Catalog number (SKU) :
ATGP2718
NCBI :
NP_001010933
Description :
Hepatocyte growth factor (HGF) regulates cell growth, cell motility, and morphogenesis by activating a tyrosine kinase signaling cascade after binding to the proto-oncogenic c-Met receptor. Hepatocyte growth factor is secreted by mesenchymal cells and acts as a multi-functional cytokine on cells of mainly epithelial origin. Its ability to stimulate mitogenesis, cell motility, and matrix invasion gives it a central role in angiogenesis, tumorogenesis, and tissue regeneration. It is secreted as a single inactive polypeptide and is cleaved by serine proteases into a 69-kDa alpha-chain and 34-kDa beta-chain. A disulfide bond between the alpha and beta chains produces the active, heterodimeric molecule. The protein belongs to the plasminogen subfamily of S1 peptidases but has no detectable protease activity. Recombinant human HGF protein was expressed in E. coli.
Alternative Names :
Hepatocyte growth factor isoform 1 preproprotein, DFNB39, F-TCF, HGFB, HPTA, SF
Concentration :
1mg/ml (determined by Bradford assay)
Formulation :
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 0.4M urea
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Wu X, Chen X, et al. (2013). Cancer Lett. 10;;335(1):128-35.
Purity :
> 80% by SDS-PAGE
Applications :
SDS-PAGE,Denatured
Antigen Species :
Human
Gene Category :
Hormones & Cytokines
Molecular Weight :
29.8 kDa (255aa)
Amino Acid Sequence :
MQRKRRNTIH EFKKSAKTTL IKIDPALKIK TKKVNTADQC ANRCTRNKGL PFTCKAFVFD KARKQCLWFP FNSMSSGVKK EFGHEFDLYE NKDYIRNCII GKGRSYKGTV SITKSGIKCQ PWSSMIPHEH SYRGKDLQEN YCRNPRGEEG GPWCFTSNPE VRYEVCDIPQ CSEVECMTCN GESYRGLMDH TESGKICQRW DHQTPHRHKF LPERYPDKGF DDNYCRNPDG QPRPWCYTLD PHTRWEYCAI KTCET
Tag :
His-Tag
Expression System :
E.coli
Product Type Name :
Recombinant Protein
UniProt No. :
P14210
Internal Search Terms :
HGF, Hepatocyte growth factor isoform 1 preproprotein, DFNB39, F-TCF, HGFB, HPTA, SF,ATGP2718-10ug,ATGP2718-20ug,ATGP2718-50ug,ATGP2718-100ug,ATGP2718-250ug,ATGP2718-500ug,ATGP2718-1mg,ATGP2718-10,ATGP2718-20,ATGP2718-50,ATGP2718-100,ATGP2718-250,ATGP2718-500,ATGP2718-1
more info or order :
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.