Recombinant HCV E2 protein | NKMAX ATGP2676 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant HCV E2 protein

catalog :

ATGP2676

quantity :

10 ug

price :

105 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant HCV E2 protein

Domain :

2634-2752aa

Catalog number (SKU) :

ATGP2676

NCBI :

NP_671491

Description :

Hepatitis C virus genotype 1 is a core protein packages viral RNA to form a viral nucleocapsid, and promotes virion budding. It modulates viral translation initiation by interacting with HCV IRES and 40S ribosomal subunit and also regulates many host cellular functions such as signaling pathways and apoptosis. It prevents the establishment of cellular antiviral state by blocking the interferon-alpha/beta (IFN-alpha/beta) and IFN-gamma signaling pathways and by inducing human STAT1 degradation. NS5B is a RNA-dependent RNA polymerase that plays an essential role in the virus replication. Recombinant HCV (Hepatitis C Virus) NS5b protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Alternative Names :

Polyprotein

Concentration :

0.25mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol, 1mM DTT

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Taylor D.R., et al. (2001) J. Virol. 75:1265-1273;; Kalliampakou K.I., et al. (2015) J. Gen. Virol. 86:1015-1025;;

Purity :

> 90% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

HCV

Gene Category :

Virus

Molecular Weight :

17 kDa (155aa) confirmed by MALDI-TOF

Amino Acid Sequence :

MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSPMGF SYDTRCFDST VTESDIRTEE AIYQCCDLDP QARVAIKSLT ERLYVGGPLT NSRGENCGYR RCRASGVLTT SCGNTLTCYI KARAACRAAG LQDCTMLVCG DDLVVICESA GVQED

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

Internal Search Terms :

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more info or order :

NKMAX product webpage