Recombinant human PKA C beta/PRKACB protein | NKMAX ATGP2666 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human PKA C beta/PRKACB protein

catalog :

ATGP2666

quantity :

20 ug

price :

80 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human PKA C beta/PRKACB protein

Domain :

1-398aa

Catalog number (SKU) :

ATGP2666

NCBI :

NP_891993

Description :

PRKACB is a member of the Ser/Thr protein kinase family and is a catalytic subunit of cAMP-dependent protein kinase. cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation of different target proteins. The inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. Recombinant human PRKACB protein, fused to His-tag at N-terminus, was expressed in E. coli.

Alternative Names :

Protein kinase cAMP-activated catalytic subunit beta, Protein kinase, cAMP-dependent, Beta catalytic subunit, PKACb

Concentration :

1mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Wu K.-J., et al. (2002) Oncogene. 21:7872-7882;; Lignitto L., et al. (2011) Nat. Cell Biol. 13:412-422;;

Purity :

> 80% by SDS-PAGE

Applications :

SDS-PAGE, Denatured

Antigen Species :

Human

Gene Category :

Signal Transduction

Molecular Weight :

48.6 kDa (421aa)

Amino Acid Sequence :

MGSSHHHHHH SSGLVPRGSH MGSMAAYREP PCNQYTGTTT ALQKLEGFAS RLFHRHSKGT AHDQKTALEN DSLHFSEHTA LWDRSMKEFL AKAKEDFLKK WENPTQNNAG LEDFERKKTL GTGSFGRVML VKHKATEQYY AMKILDKQKV VKLKQIEHTL NEKRILQAVN FPFLVRLEYA FKDNSNLYMV MEYVPGGEMF SHLRRIGRFS EPHARFYAAQ IVLTFEYLHS LDLIYRDLKP ENLLIDHQGY IQVTDFGFAK RVKGRTWTLC GTPEYLAPEI ILSKGYNKAV DWWALGVLIY EMAAGYPPFF ADQPIQIYEK IVSGKVRFPS HFSSDLKDLL RNLLQVDLTK RFGNLKNGVS DIKTHKWFAT TDWIAIYQRK VEAPFIPKFR GSGDTSNFDD YEEEDIRVSI TEKCAKEFGE F

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

P22694

Internal Search Terms :

PRKACB, Protein kinase cAMP-dependent catalytic beta, Protein kinase, cAMP-dependent, catalytic, beta, PKACB,ATGP2666-10ug,ATGP2666-20ug,ATGP2666-50ug,ATGP2666-100ug,ATGP2666-250ug,ATGP2666-500ug,ATGP2666-1mg,ATGP2666-10,ATGP2666-20,ATGP2666-50,ATGP2666-100,ATGP2666-250,ATGP2666-500,ATGP2666-1

more info or order :

NKMAX product webpage