Recombinant human MESDC1 protein | NKMAX ATGP2657 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human MESDC1 protein

catalog :

ATGP2657

quantity :

20 ug

price :

80 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human MESDC1 protein

Domain :

1-362aa

Catalog number (SKU) :

ATGP2657

NCBI :

NP_072088

Description :

Mesoderm development candidate 1, also known as MESDC1, belongs to the MESD family. It is a 362 amino acid protein encoded by a gene that maps to human chromosome 15q25. 1. MESDC1 acts as a chaperone for low-density lipoprotein receptor (LDLR) proteins in the ER, and particularly associates with Wnt signaling pathway coreceptors LRP5 and LPR6). MESDC1 is required for proper LRP5/6 folding and maturation to the cell surface, which plays a major role in Wnt signaling. Recombinant human MESDC1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Alternative Names :

Mesoderm development candidate 1, MGC99595

Concentration :

0.5mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 10% glycerol, 1mM DTT

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Wines M E., et al. (2001) Genomics.72: 88-98.;; Midia G S., et al. (2008) JAAPA. 21: 21-25.;;

Purity :

> 95% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Development

Molecular Weight :

40.1 kDa (385aa) confirmed by MALDI-TOF

Amino Acid Sequence :

MGSSHHHHHH SSGLVPRGSH MGSMASGSAG KPTGEAASPA PASAIGGASS QPRKRLVSVC DHCKGKMQLV ADLLLLSSEA RPVLFEGPAS SGAGAESFEQ CRDTIIARTK GLSILTHDVQ SQLNMGRFGE AGDSLVELGD LVVSLTECSA HAAYLAAVAT PGAQPAQPGL VDRYRVTRCR HEVEQGCAVL RATPLADMTP QLLLEVSQGL SRNLKFLTDA CALASDKSRD RFSREQFKLG VKCMSTSASA LLACVREVKV APSELARSRC ALFSGPLVQA VSALVGFATE PQFLGRAAAV SAEGKAVQTA ILGGAMSVVS ACVLLTQCLR DLAQHPDGGA KMSDHRERLR NSACAVSEGC TLLSQALRER SSPRTLPPVN SNSVN

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

Q9H1K6

Internal Search Terms :

MESDC1, Mesoderm development candidate 1, MGC99595,ATGP2657-10ug,ATGP2657-20ug,ATGP2657-50ug,ATGP2657-100ug,ATGP2657-250ug,ATGP2657-500ug,ATGP2657-1mg,ATGP2657-10,ATGP2657-20,ATGP2657-50,ATGP2657-100,ATGP2657-250,ATGP2657-500,ATGP2657-1

more info or order :

NKMAX product webpage