Recombinant human GLUD1 protein | NKMAX ATGP2653 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human GLUD1 protein

catalog :

ATGP2653

quantity :

20 ug

price :

80 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human GLUD1 protein

Domain :

54-558aa

Catalog number (SKU) :

ATGP2653

NCBI :

NP_005262

Description :

Glutamate dehydrogenase 1, mitochondrial precursor, also known as GLuD1, belongs to the Glu/Leu/Phe/Val dehydrogenases family. GLuD1 has a central role in nitrogen metabolism in plants and animals. GLuD1 is found in all organisms and catalyzes the oxidative deamination of 1-glutamate to 2-oxoglutarate. Mutations in the gene encoding GLuD1 causes hyperinsulinism-hyperammonemia syndrome (HHS), which is an inherited condition characterized by high insulin and ammonia levels in the blood. GLuD1 may also be involved in learning and memory reactions by increasing the turnover of the excitatory neurotransmitter glutamate. Recombinant human GLuD1 protein, fused to His-tag at N-terminus, was expressed in E. coli.

Alternative Names :

Glutamate dehydrogenase 1, mitochondrial, GDH, GDH1, GLUD

Concentration :

1mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Mastorodemos V., et al. (2009) Biochem Cell Biol. 87:505-516.;; Tanizawa Y., et al. (2002) Diabetes. 51:712-717.;;

Purity :

> 80% by SDS-PAGE

Applications :

SDS-PAGE, Denatured

Antigen Species :

Human

Gene Category :

Metabolism

Molecular Weight :

58.4 kDa (528aa)

Amino Acid Sequence :

SEAVADR EDDPNFFKMV EGFFDRGASI VEDKLVEDLR TRESEEQKRN RVRGILRIIK PCNHVLSLSF PIRRDDGSWE VIEGYRAQHS QHRTPCKGGI RYSTDVSVDE VKALASLMTY KCAVVDVPFG GAKAGVKINP KNYTDNELEK ITRRFTMELA KKGFIGPGID VPAPDMSTGE REMSWIADTY ASTIGHYDIN AHACVTGKPI SQGGIHGRIS ATGRGVFHGI ENFINEASYM SILGMTPGFG DKTFVVQGFG NVGLHSMRYL HRFGAKCIAV GESDGSIWNP DGIDPKELED FKLQHGSILG FPKAKPYEGS ILEADCDILI PAASEKQLTK SNAPRVKAKI IAEGANGPTT PEADKIFLER NIMVIPDLYL NAGGVTVSYF EWLKNLNHVS YGRLTFKYER DSNYHLLMSV QESLERKFGK HGGTIPIVPT AEFQDRISGA SEKDIVHSGL AYTMERSARQ IMRTAMKYNL GLDLRTAAYV NAIEKVFKVY NEAGVTFT

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

P00367

Internal Search Terms :

GLuD1, Glutamate dehydrogenase 1 mitochondrial, Glutamate dehydrogenase 1, mitochondrial, GDH, GDH1, GLuD,ATGP2653-10ug,ATGP2653-20ug,ATGP2653-50ug,ATGP2653-100ug,ATGP2653-250ug,ATGP2653-500ug,ATGP2653-1mg,ATGP2653-10,ATGP2653-20,ATGP2653-50,ATGP2653-100,ATGP2653-250,ATGP2653-500,ATGP2653-1

more info or order :

NKMAX product webpage