product summary
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company name :
NKMAX
product type :
protein
product name :
Recombinant human Caspase-3 protein
catalog :
ATGP2651
quantity :
10 ug
price :
110 USD
more info or order :
NKMAX product webpage
product information
Product Type :
Proteins
Item Name :
Recombinant human Caspase-3 protein
Domain :
176-277aa
Catalog number (SKU) :
ATGP2651
NCBI :
NP_116786
Description :
CASP3 is a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. Recombinant human CASP3 protein, fused to His-tag at N-terminus, was expressed in E. coli.
Alternative Names :
Caspase 3, CPP32, CPP32B, SCA-1
Concentration :
0.5mg/ml (determined by Bradford assay)
Formulation :
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Harrington HA, Ho KL, et al. (2008). Theor Biol Med Model. 10;;5:26.
Purity :
> 80% by SDS-PAGE
Applications :
SDS-PAGE
Antigen Species :
Human
Gene Category :
Apoptosis
Molecular Weight :
12 kDa (103aa)
Amino Acid Sequence :
MSGVDDDMAC HKIPVEADFL YAYSTAPGYY SWRNSKDGSW FIQSLCAMLK QYADKLEFMH ILTRVNRKVA TEFESFSFDA TFHAKKQIPC IVSMLTKELY FYH
Tag :
Non-Tagged
Expression System :
E.coli
Product Type Name :
Recombinant Protein
UniProt No. :
P42574
Internal Search Terms :
Caspase3, Caspase 3, CPP32, CPP32B, SCA-1,ATGP2651-10ug,ATGP2651-20ug,ATGP2651-50ug,ATGP2651-100ug,ATGP2651-250ug,ATGP2651-500ug,ATGP2651-1mg,ATGP2651-10,ATGP2651-20,ATGP2651-50,ATGP2651-100,ATGP2651-250,ATGP2651-500,ATGP2651-1
more info or order :
NKMAX product webpage
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.