Recombinant human CD30 Ligand/TNFSF8 protein | NKMAX ATGP2649 product information

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product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human CD30 Ligand/TNFSF8 protein

catalog :

ATGP2649

quantity :

20 ug

price :

80 USD

product information

Product Type :

Proteins

Item Name :

Recombinant human CD30 Ligand/TNFSF8 protein

Domain :

63-234aa

Catalog number (SKU) :

ATGP2649

NCBI :

NP_001235

Description :

TNFSF8 is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF8/CD30, which is a cell surface antigen and a marker for Hodgkin lymphoma and related hematologic malignancies. The engagement of this cytokine expressed on B cell surface plays an inhibitory role in modulating Ig class switch. TNFSF8 was shown to enhance cell proliferation of some lymphoma cell lines, while to induce cell death and reduce cell proliferation of other lymphoma cell lines. The pleiotropic biologic activities of this cytokine on different CD30+ lymphoma cell lines may play a pathophysiologic role in Hodgkin's and some non-Hodgkin's lymphomas. Recombinant human TNFSF8 protein, fused to His-tag at N-terminus, was expressed in E. coli.

Alternative Names :

tumor necrosis factor ligand superfamily member 8, CD153, CD30L, CD30LG

Concentration :

0.5mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 0.4M urea

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Smith C.A., et al (1993). Armitage R.J. Cell 73:1349-1360;; Croager E.J., et al (1997). Biochim. Biophys. Acta 1353:231-235;;

Purity :

> 80% by SDS-PAGE

Applications :

SDS-PAGE,Denatured

Antigen Species :

Human

Gene Category :

Immunology

Molecular Weight :

22.0 kDa (195aa)

Bioassay Procedure :

MGSSHHHHHH SSGLVPRGSH MGSQRTDSIP NSPDNVPLKG GNCSEDLLCI LKRAPFKKSW AYLQVAKHLN KTKLSWNKDG ILHGVRYQDG NLVIQFPGLY FIICQLQFLV QCPNNSVDLK LELLINKHIK KQALVTVCES GMQTKHVYQN LSQFLLDYLQ VNTTISVNVD TFQYIDTSTF PLENVLSIFL YSNSD

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

P32971

Internal Search Terms :

CD30 Ligand, TNFSF8, tumor necrosis factor ligand superfamily member 8, CD153, CD30L, CD30LG

Size 1 :

20 ug

Price 1 (USD) :

80 USD