product summary
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company name :
NKMAX
product type :
protein
product name :
Recombinant human Sirtuin 1/SIRT1 protein
catalog :
ATGP2625
quantity :
20 ug
price :
80 USD
more info or order :
product information
Product Type :
Proteins
Item Name :
Recombinant human Sirtuin 1/SIRT1 protein
Domain :
254-495aa
Catalog number (SKU) :
ATGP2625
NCBI :
NP_036370
Description :
SIRT1 is a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. Alternative splicing results in multiple transcript variants. Recombinant human SIRT1 protein, fused to His-tag at N-terminus, was expressed in E. coli.
Alternative Names :
NAD-dependent protein deacetylase sirtuin-1, Regulatory protein SIR2 homolog 1, SIR2-like protein 1, hSIR2, SIR2L1, Sirtuin, Silent mating type information regulation 2 homolog 1 (S. cerevisiae)
Concentration :
0.5mg/ml (determined by Bradford assay)
Formulation :
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 0.4M urea
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Langley E., et al. (2002) EMBO J. 21:2383-2396.
Purity :
> 90% by SDS-PAGE
Applications :
SDS-PAGE, Denatured
Antigen Species :
Human
Gene Category :
Epigenomics (Transcription & Translation)
Molecular Weight :
31.6 kDa (280aa)
Amino Acid Sequence :
MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSHMKK IIVLTGAGVS VSCGIPDFRS RDGIYARLAV DFPDLPDPQA MFDIEYFRKD PRPFFKFAKE IYPGQFQPSL CHKFIALSDK EGKLLRNYTQ NIDTLEQVAG IQRIIQCHGS FATASCLICK YKVDCEAVRG DIFNQVVPRC PRCPADEPLA IMKPEIVFFG ENLPEQFHRA MKYDKDEVDL LIVIGSSLKV RPVALIPSSI PHEVPQILIN REPLPHLHFD VELLGDCDVI INELCHRLGG
Tag :
His-Tag
Expression System :
E.coli
Product Type Name :
Recombinant Protein
UniProt No. :
Q96EB6
Internal Search Terms :
Sirtuin1, SIRT1, Sirtuin 1, Sirtuin (silent mating type information regulation 2 homolog) 1 (S. cerevisiae), SIR2L1,ATGP2625-10ug,ATGP2625-20ug,ATGP2625-50ug,ATGP2625-100ug,ATGP2625-250ug,ATGP2625-500ug,ATGP2625-1mg,ATGP2625-10,ATGP2625-20,ATGP2625-50,ATGP2625-100,ATGP2625-250,ATGP2625-500,ATGP2625-1
more info or order :
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.