protein

Recombinant human IRF5 protein

ATGP2617

10 ug

130 USD

Recombinant human IRF5 protein

176-240aa

ATGP2617

NP_116032.1

IRF5 is a member of the interferon regulatory factor (IRF) family, a group of transcription factors with diverse roles, including virus-mediated activation of interferon, and modulation of cell growth, differentiation, apoptosis, and immune system activity. Members of the IRF family are characterized by a conserved N-terminal DNA-binding domain containing tryptophan (W) repeats. Multiple transcript variants encoding different isoforms have been found for this gene, and a 30-nt indel polymorphism Recombinant human IRF5 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

interferon regulatory factor 5 isoform b, SLEB10

0.25mg/ml (determined by Bradford assay)

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 30% glycerol, 1mM DTT

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Barnes B.J., et al (2001). J. Biol. Chem. 276:23382-23390;; Schoenemeyer A., et al (2005). J. Biol. Chem. 280:17005-17012;;

> 85% by SDS-PAGE

SDS-PAGE

Human

Epigenomics (Transcription & Translation)

10.7 kDa (101aa) confirmed by MALDI-TOF

PPTL QPPTLQPPVV LGPPAPDPSP LAPPPGNPAG FRELLSEVLE PGPLPASLPP AGEQLLPDLL I

His-Tag

E.coli

Recombinant Protein

Q13568

IRF5, interferon regulatory factor 5 isoform b, SLEB10,ATGP2617-10ug,ATGP2617-20ug,ATGP2617-50ug,ATGP2617-100ug,ATGP2617-250ug,ATGP2617-500ug,ATGP2617-1mg,ATGP2617-10,ATGP2617-20,ATGP2617-50,ATGP2617-100,ATGP2617-250,ATGP2617-500,ATGP2617-1

Yeon SI, et al. Development of monoclonal antibodies against human IRF-5 and their use in identifying the binding of IRF-5 to nuclear import proteins karyopherin-alpha1 and -beta1. Yonsei Med J. 2008 Dec 31;49(6):1023-31.{https://pubmed.ncbi.nlm.nih.gov/19108028/}