protein

Recombinant human Glypican 4 protein

ATGP2616

10 ug

105 USD

Recombinant human Glypican 4 protein

401-529aa

ATGP2616

NP_001439.2

Glypican 4, also known as GPC4, is a family of glycosylphosphatidylinositol (GPI) -anchored heparan sulphate proteoglycans (HSPGs) that may play a role in the control of cell division and growth regulation. GPC4 is widely expressed in human tissues, including lung, kidney, heart, placenta, skeletal muscle, and pancreas. GPC4 has also been shown to be present in astrocytes, haematopoietic-progenitor and bone-marrow-stromal cells. Recombinant human GPC4 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Glypican 4, Glypican 4, dJ900E8.1, glypican proteoglycan 4

0.25mg/ml (determined by Bradford assay)

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 10% glycerol

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Fico A., et al. (2012) Stem Cells. 30(9): 1863-74.;; Ybot Gonzalez P., et al. (2005) Dev Dyn. 233(3): 1013-7.;;

> 85% by SDS-PAGE

SDS-PAGE

Human

Stem cell

18 kDa (165aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)

SSLP SNVCNDERMA AGNGNEDDCW NGKGKSRYLF AVTGNGLANQ GNNPEVQVDT SKPDILILRQ IMALRVMTSK MKNAYNGNDV DFFDISDESS GEGSGSGCEY QQCPSEFDYN ATDHAGKSAN EKADS

His-Tag

E.coli

Recombinant Protein

O75487

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Nakashima Y, et al. Atorvastatin Inhibits the HIF1α-PPAR Axis, Which Is Essential for Maintaining the Function of Human Induced Pluripotent Stem Cells. (Mol Ther. 2018){https://pubmed.ncbi.nlm.nih.gov/29929789/}