Recombinant human CD40/TNFRSF5 protein | NKMAX ATGP2615 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human CD40/TNFRSF5 protein

catalog :

ATGP2615

quantity :

10 ug

price :

80 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human CD40/TNFRSF5 protein

Domain :

21-193aa

Catalog number (SKU) :

ATGP2615

NCBI :

NP_001241.1

Description :

CD40 is a member of the TNF-receptor superfamily. This receptor has been found to be essential in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. AT-hook transcription factor AKNA is reported to coordinately regulate the expression of this receptor and its ligand, which may be important for homotypic cell interactions. Adaptor protein TNFR2 interacts with this receptor and serves as a mediator of the signal transduction. The interaction of this receptor and its ligand is found to be necessary for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis. Recombinant human CD40 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Alternative Names :

Tumor necrosis factor receptor superfamily member 5, B-cell surface antigen CD40, Bp50, p50, CD40L receptor, CDw40

Concentration :

0.25mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol, 1mM DTT

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Tone M., et al. (2001) Proc. Natl. Acad. Sci. u.S.A. 98:1751-1756;; Khandekar S.S., et al. (2001) Protein Expr. Purif. 23:301-310;;

Purity :

> 90% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Stem cell

Molecular Weight :

21.6 kDa (196aa) confirmed by MALDI-TOF

Amino Acid Sequence :

EPPTACR EKQYLINSQC CSLCQPGQKL VSDCTEFTET ECLPCGESEF LDTWNRETHC HQHKYCDPNL GLRVQQKGTS ETDTICTCEE GWHCTSEACE SCVLHRSCSP GFGVKQIATG VSDTICEPCP VGFFSNVSSA FEKCHPWTSC ETKDLVVQQA GTNKTDVVCG PQDRLR

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

P25942

Internal Search Terms :

CD40, TNFRSF5, CD40 molecule TNF receptor superfamily member 5, CD40 molecule, TNF receptor superfamily member 5, Bp50, CDW40, p50, TNFRSF5,ATGP2615-10ug,ATGP2615-20ug,ATGP2615-50ug,ATGP2615-100ug,ATGP2615-250ug,ATGP2615-500ug,ATGP2615-1mg,ATGP2615-10,ATGP2615-20,ATGP2615-50,ATGP2615-100,ATGP2615-250,ATGP2615-500,ATGP2615-1

more info or order :

NKMAX product webpage