Recombinant human BEST1 protein | NKMAX ATGP2600 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human BEST1 protein

catalog :

ATGP2600

quantity :

20 ug

price :

80 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human BEST1 protein

Domain :

292-585aa

Catalog number (SKU) :

ATGP2600

NCBI :

NP_004174.1

Description :

BEST1 is a member of the bestrophin gene family. This small gene family is characterized by proteins with a highly conserved N-terminus with four to six transmembrane domains. Bestrophins may form chloride ion channels or may regulate voltage-gated L-type calcium-ion channels. Bestrophins are generally believed to form calcium-activated chloride-ion channels in epithelial cells but they have also been shown to be highly permeable to bicarbonate ion transport in retinal tissue. Mutations in this gene are responsible for juvenile-onset vitelliform macular dystrophy (VMD2), also known as Best macular dystrophy, in addition to adult-onset vitelliform macular dystrophy (AVMD) and other retinopathies. Recombinant human BEST1 protein, fused to His-tag at N-terminus, was expressed in E. coli

Alternative Names :

Bestrophin-1 isoform 1, ARB, BEST, BMD, RP50, Tu15B, VMD2

Concentration :

1mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Sodi A, Passerini I, et al. (2012). Mol Vis.18:2736-48.;; Bitner H, Schatz P, et al. (2012). Am J Ophthalmol. 154(2):403-412.;;

Purity :

> 90% by SDS-PAGE

Applications :

SDS-PAGE, Denatured

Antigen Species :

Human

Gene Category :

Neuroscience

Molecular Weight :

36 kDa (317aa)

Amino Acid Sequence :

EQLINPF GEDDDDFETN WIVDRNLQVS LLAVDEMHQD LPRMEPDMYW NKPEPQPPYT AASAQFRRAS FMGSTFNISL NKEEMEFQPN QEDEEDAHAG IIGRFLGLQS HDHHPPRANS RTKLLWPKRE SLLHEGLPKN HKAAKQNVRG QEDNKAWKLK AVDAFKSAPL YQRPGYYSAP QTPLSPTPMF FPLEPSAPSK LHSVTGIDTK DKSLKTVSSG AKKSFELLSE SDGALMEHPE VSQVRRKTVE FNLTDMPEIP ENHLKEPLEQ SPTNIHTTLK DHMDPYWALE NRDEAHS

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

O76090

Internal Search Terms :

BEST1, Bestrophin-1 isoform 1, ARB, BEST, BMD, RP50, Tu15B, VMD2,ATGP2600-10ug,ATGP2600-20ug,ATGP2600-50ug,ATGP2600-100ug,ATGP2600-250ug,ATGP2600-500ug,ATGP2600-1mg,ATGP2600-10,ATGP2600-20,ATGP2600-50,ATGP2600-100,ATGP2600-250,ATGP2600-500,ATGP2600-1

more info or order :

NKMAX product webpage