Recombinant human DOK4 protein | NKMAX ATGP2595 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human DOK4 protein

catalog :

ATGP2595

quantity :

20 ug

price :

80 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human DOK4 protein

Domain :

1-326aa

Catalog number (SKU) :

ATGP2595

NCBI :

NP_060580

Description :

DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK4 functions in RET-mediated neurite outgrowth and plays a positive role in activation of the MAP kinase pathway. This protein is putative link with downstream effectors of RET in neuronal differentiation. DOK4 may be involved in the regulation of the immune response induced by T-cells. Recombinant human DOK4 protein, fused to His-tag at N-terminus, was expressed in E. coli.

Alternative Names :

docking protein 4, Downstream of tyrosine kinase 4, FLJ10488, IRS-5, IRS5

Concentration :

1mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.4M uREA, 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Hooker,E, et al. (2012) Biochem. Biophys. Res. Commun. 427 (1), 67-72;; Gerard,A., et al. (2009) J. Immunol. 182 (12), 7681-7689;;

Purity :

> 85% by SDS-PAGE

Applications :

SDS-PAGE,Denatured

Antigen Species :

Human

Gene Category :

Signal Transduction

Molecular Weight :

39.4 kDa (349aa)

Amino Acid Sequence :

MGSSHHHHHH SSGLVPRGSH MGSMATNFSD IVKQGYVKMK SRKLGIYRRC WLVFRKSSSK GPQRLEKYPD EKSVCLRGCP KVTEISNVKC VTRLPKETKR QAVAIIFTDD SARTFTCDSE LEAEEWYKTL SVECLGSRLN DISLGEPDLL APGVQCEQTD RFNVFLLPCP NLDVYGECKL QITHENIYLW DIHNPRVKLV SWPLCSLRRY GRDATRFTFE AGRMCDAGEG LYTFQTQEGE QIYQRVHSAT LAIAEQHKRV LLEMEKNVRL LNKGTEHYSY PCTPTTMLPR SAYWHHITGS QNIAEASSYA GEGYGAAQAS SETDLLNRFI LLKPKPSQGD SSEAKTPSQ

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

Q8TEW6

Internal Search Terms :

DOK4, docking protein 4, Downstream of tyrosine kinase 4, FLJ10488, IRS-5, IRS5,ATGP2595-10ug,ATGP2595-20ug,ATGP2595-50ug,ATGP2595-100ug,ATGP2595-250ug,ATGP2595-500ug,ATGP2595-1mg,ATGP2595-10,ATGP2595-20,ATGP2595-50,ATGP2595-100,ATGP2595-250,ATGP2595-500,ATGP2595-1

more info or order :

NKMAX product webpage