product summary
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company name :
NKMAX
product type :
protein
product name :
Recombinant human IYD protein
catalog :
ATGP2592
quantity :
20 ug
price :
80 USD
more info or order :
product information
Product Type :
Proteins
Item Name :
Recombinant human IYD protein
Domain :
24-214aa
Catalog number (SKU) :
ATGP2592
NCBI :
NP_001158167
Description :
IYD is an enzyme that catalyzes the oxidative NADPH-dependent deiodination of mono- and diiodotyrosine, which are the halogenated byproducts of thyroid hormone production. The N-terminus of the protein functions as a membrane anchor. Mutations in this gene cause congenital hypothyroidism due to dyshormonogenesis type 4, which is also referred to as deiodinase deficiency, or iodotyrosine dehalogenase deficiency, or thyroid hormonogenesis type 4. Alternative splicing results in multiple transcript variants. Recombinant human IYD protein, fused to His-tag at N-terminus, was expressed in E. coli.
Alternative Names :
iodotyrosine dehalogenase 1 isoform 3, C6orf71, DEHAL1, dJ422F24.1, TDH4
Concentration :
1mg/ml (determined by Bradford assay)
Formulation :
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.4M uREA, 10% glycerol
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Burniat,A, et al. (2012) J. Clin. Endocrinol. Metab. 97 (7), E1276-E1283;; Belevich,V.K., et al. (2011) Biomed Khim 57 (2), 187-194;;
Purity :
> 90% by SDS-PAGE
Applications :
SDS-PAGE
Antigen Species :
Human
Gene Category :
Cardiovascular
Molecular Weight :
25.1 kDa (214aa)
Amino Acid Sequence :
DRSMEKK KGEPRTRAEA RPWVDEDLKD SSDLHQAEED ADEWQESEEN VEHIPFSHNH YPEKEMVKRS QEFYELLNKR RSVRFISNEQ VPMEVIDNVI RTAGTAPSGA HTEPWTFVVV KDPDVKHKIR KIIEEEEEIN YMKRMGHRWV TDLKKLRTNW IKEYLDTAPI LILIFKQVHG FAANGKKKVH YYNE
Tag :
His-Tag
Expression System :
E.coli
Product Type Name :
Recombinant Protein
UniProt No. :
Q6PHW0
Internal Search Terms :
IYD, iodotyrosine dehalogenase 1 isoform 3, C6orf71, DEHAL1, dJ422F24.1, TDH4,ATGP2592-10ug,ATGP2592-20ug,ATGP2592-50ug,ATGP2592-100ug,ATGP2592-250ug,ATGP2592-500ug,ATGP2592-1mg,ATGP2592-10,ATGP2592-20,ATGP2592-50,ATGP2592-100,ATGP2592-250,ATGP2592-500,ATGP2592-1
more info or order :
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.