Recombinant human Cathepsin E protein | NKMAX ATGP2586 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human Cathepsin E protein

catalog :

ATGP2586

quantity :

20 ug

price :

80 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human Cathepsin E protein

Domain :

57-363aa

Catalog number (SKU) :

ATGP2586

NCBI :

NP_683865

Description :

CTSE is a gastric aspartyl protease that functions as a disulfide-linked homodimer. CTSE, which is a member of the peptidase C1 family, has a specificity similar to that of pepsin A and cathepsin D. It is an intracellular proteinase that does not appear to be involved in the digestion of dietary protein and is found in highest concentration in the surface of epithelial mucus-producing cells of the stomach. It is the first aspartic proteinase expressed in the fetal stomach and is found in more than half of gastric cancers. It appears, therefore, to be an oncofetal antigen. Transcript variants utilizing alternative polyadenylation signals and two transcript variants encoding different isoforms exist for this gene. Recombinant human CTSE protein, fused to His-tag at N-terminus, was expressed in E. coli.

Alternative Names :

Cathepsin E, CATE, CTSE

Concentration :

1mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Sealy L., et al. (1996) Eur. J. Immunol. 26:1838-1843;; Cook M., et al. (2001) Eur. J. Biochem. 268:2658-2668;;

Purity :

> 85% by SDS-PAGE

Applications :

SDS-PAGE, Denatured

Antigen Species :

Human

Gene Category :

Immunology

Molecular Weight :

35.4 kDa (330aa)

Amino Acid Sequence :

TESCSMD QSAKEPLINY LDMEYFGTIS IGSPPQNFTV IFDTGSSNLW VPSVYCTSPA CKTHSRFQPS QSSTYSQPGQ SFSIQYGTGS LSGIIGADQV SVEGLTVVGQ QFGESVTEPG QTFVDAEFDG ILGLGYPSLA VGGVTPVFDN MMAQNLVDLP MFSVYMSSNP EGGAGSELIF GGYDHSHFSG SLNWVPVTKQ AYWQIALDNM LWSVPTLTSC RMSPSPLTES PIPSAQLPTP YWTSWMECSS AAVAFKDLTS TLQLGPSGSW GMSSFDSFTQ SLTVGITVWD WPQQSPKEGP CVCACLSDRP

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

P14091

Internal Search Terms :

CTSE, Cathepsin E, CATE,ATGP2586-10ug,ATGP2586-20ug,ATGP2586-50ug,ATGP2586-100ug,ATGP2586-250ug,ATGP2586-500ug,ATGP2586-1mg,ATGP2586-10,ATGP2586-20,ATGP2586-50,ATGP2586-100,ATGP2586-250,ATGP2586-500,ATGP2586-1

more info or order :

NKMAX product webpage