Recombinant human MMP-3 protein | NKMAX ATGP2576 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human MMP-3 protein

catalog :

ATGP2576

quantity :

4 ug

price :

80 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human MMP-3 protein

Domain :

100-477aa

Catalog number (SKU) :

ATGP2576

NCBI :

NP_002413

Description :

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. MMP3 is an enzyme which degrades fibronectin, laminin, collagens III, IV, IX, and X, and cartilage proteoglycans. The enzyme is thought to be involved in wound repair, progression of atherosclerosis, and tumor initiation. Recombinant human MMP3 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Alternative Names :

Matrix metallopeptidase 3, CHDS6, MMP-3, SL-1, STMY, STMY1, STR1

Concentration :

0.25mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Nagase H., et al. (1990) Biochemistry. 29:5783-5789;; Ye S., et al. (1996) J. Biol. Chem. 271:13055-13060;;

Purity :

> 90% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Cancer

Molecular Weight :

45.2 kDa (401aa) confirmed by MALDI-TOF

Amino Acid Sequence :

MGSSHHHHHH SSGLVPRGSH MGSFRTFPGI PKWRKTHLTY RIVNYTPDLP KDAVDSAVEK ALKVWEEVTP LTFSRLYEGE ADIMISFAVR EHGDFYPFDG PGNVLAHAYA PGPGINGDAH FDDDEQWTKD TTGTNLFLVA AHEIGHSLGL FHSANTEALM YPLYHSLTDL TRFRLSQDDI NGIQSLYGPP PDSPETPLVP TEPVPPEPGT PANCDPALSF DAVSTLRGEI LIFKDRHFWR KSLRKLEPEL HLISSFWPSL PSGVDAAYEV TSKDLVFIFK GNQFWAIRGN EVRAGYPRGI HTLGFPPTVR KIDAAISDKE KNKTYFFVED KYWRFDEKRN SMEPGFPKQI AEDFPGIDSK IDAVFEEFGF FYFFTGSSQL EFDPNAKKVT HTLKSNSWLN C

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

P08254

Internal Search Terms :

MMP3, Matrix metallopeptidase 3, CHDS6, MMP-3, SL-1, STMY, STMY1, STR1,ATGP2576-10ug,ATGP2576-20ug,ATGP2576-50ug,ATGP2576-100ug,ATGP2576-250ug,ATGP2576-500ug,ATGP2576-1mg,ATGP2576-10,ATGP2576-20,ATGP2576-50,ATGP2576-100,ATGP2576-250,ATGP2576-500,ATGP2576-1

more info or order :

NKMAX product webpage