Recombinant human CHRNA6 protein | NKMAX ATGP2572 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human CHRNA6 protein

catalog :

ATGP2572

quantity :

20 ug

price :

80 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human CHRNA6 protein

Domain :

26-239aa

Catalog number (SKU) :

ATGP2572

NCBI :

NP_004189

Description :

Cholinergic receptor, nicotinic, alpha 6, also known as CHRNA6, belongs to the nicotinic acetylcholine receptors (nAChRs) family. nAChRs are heteropentameric ligand-gated ion channels resulting from the assembly of alpha and beta protein subunits. This ion channel is gated by the binding of acetylcholine to the assembled receptor. Alpha 6 is often found associated with beta 3, beta 2, and alpha 4 subunits. CHRNA6 receptors have a relatively selective localization to the nigrostriatal pathway where they function to mediate dopamine release. Recombinant human CHRNA6 protein, fused to His-tag at N-terminus, was expressed in E. coli.

Alternative Names :

Cholinergic receptor nicotinic alpha, Cholinergic receptor, nicotinic, alpha, CHNRA6

Concentration :

1mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Keskitalo Vuokko k., et al. (2011) Nicotine Tob Res. 13(8): 686-90.;; Groot Kormrlink P J., et al. (2004) J Gen Physiol. 123: 697-708.;;

Purity :

> 85% by SDS-PAGE

Applications :

SDS-PAGE,Denatured

Antigen Species :

Human

Gene Category :

Neuroscience

Molecular Weight :

29.3 kDa (250aa)

Amino Acid Sequence :

MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSKGCV GCATEERLFH KLFSHYNQFI RPVENVSDPV TVHFEVAITQ LANVDEVNQI METNLWLRHI WNDYKLRWDP MEYDGIETLR VPADKIWKPD IVLYNNAVGD FQVEGKTKAL LKYNGMITWT PPAIFKSSCP MDITFFPFDH QNCSLKFGSW TYDKAEIDLL IIGSKVDMND FWENSEWEII DASGYKHDIK YNCCEEIYTD ITYSFYIRRL

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

Q15825

Internal Search Terms :

CHRNA6, Cholinergic receptor nicotinic alpha, Cholinergic receptor, nicotinic, alpha, CHNRA6,ATGP2572-10ug,ATGP2572-20ug,ATGP2572-50ug,ATGP2572-100ug,ATGP2572-250ug,ATGP2572-500ug,ATGP2572-1mg,ATGP2572-10,ATGP2572-20,ATGP2572-50,ATGP2572-100,ATGP2572-250,ATGP2572-500,ATGP2572-1

more info or order :

NKMAX product webpage