Recombinant human Apolipoprotein C1/APOC1 protein | NKMAX ATGP2554 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human Apolipoprotein C1/APOC1 protein

catalog :

ATGP2554

quantity :

10 ug

price :

105 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human Apolipoprotein C1/APOC1 protein

Domain :

27-83aa

Catalog number (SKU) :

ATGP2554

NCBI :

NP_001636.1

Description :

APOC1 is a member of the apolipoprotein C family. This gene is expressed primarily in the liver, and it is activated when monocytes differentiate into macrophages. A pseudogene of this gene is located 4 kb downstream in the same orientation, on the same chromosome. It is mapped to chromosome 19, where it resides within an apolipoprotein gene cluster. Alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined. APOC1 has a length of 57 amino acids normally found in plasma and responsible for the activation of esterified lechitin cholesterol with an important role in the exchange of esterified cholesterol between lipoproteins and in removal of cholesterol from tissues. Its main function is inhibition of CETP, probably by altering the electric charge of HDL molecules. Recombinant human APOC1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Alternative Names :

Apolipoprotein C-I precursor, Apolipoprotein C-I precursor, APOC1B, Apo-CIB, ApoC-IB, Apolipoprotein C-I, Apolipoprotein C1

Concentration :

0.25mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Gautier T, Masson D, et al. (2000). J Biol Chem. 1;;275(48):37504-9.;; Kamino K, Yoshiiwa A, et al. (1996). Gerontology. Suppl 1:12-9.;;

Purity :

> 85% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Metabolism

Molecular Weight :

9 kDa (80aa) confirmed by MALDI-TOF

Amino Acid Sequence :

TPDVSSA LDKLKEFGNT LEDKARELIS RIKQSELSAK MREWFSETFQ KVKEKLKIDS

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

P02654

Internal Search Terms :

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more info or order :

NKMAX product webpage