Recombinant human MMP-8 protein | NKMAX ATGP2543 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human MMP-8 protein

catalog :

ATGP2543

quantity :

20 ug

price :

80 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human MMP-8 protein

Domain :

101-467aa

Catalog number (SKU) :

ATGP2543

NCBI :

NP_002415.1

Description :

MMP8 protein of the matrix metalloproteinase (MMP) family is involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the enzyme encoded by this gene is stored in secondary granules within neutrophils and is activated by autolytic cleavage. Its function is degradation of type I, II and III collagens. MMP8 is part of a cluster of MMP. Recombinant human MMP8 protein, fused to His-tag at N-terminus, was expressed in E. coli.

Alternative Names :

Neutrophil collagenase preproprotein, CLG1, HNC, MMP-8, PMNL-CL, Matrix metalloproteinase-8, MMP-8, PMNL collagenase

Concentration :

1mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 0.4M urea

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Hasty K.A., et al (1990). J. Biol. Chem. 265:11421-11424;; Betz M., et al (1997). Eur. J. Biochem. 247:356-363;;

Purity :

> 85% by SDS-PAGE

Applications :

SDS-PAGE, Denatured

Antigen Species :

Human

Gene Category :

Cancer

Molecular Weight :

44.3 kDa (390aa)

Amino Acid Sequence :

LTPGNPK WERTNLTYRI RNYTPQLSEA EVERAIKDAF ELWSVASPLI FTRISQGEAD INIAFYQRDH GDNSPFDGPN GILAHAFQPG QGIGGDAHFD AEETWTNTSA NYNLFLVAAH EFGHSLGLAH SSDPGALMYP NYAFRETSNY SLPQDDIDGI QAIYGLSSNP IQPTGPSTPK PCDPSLTFDA ITTLRGEILF FKDRYFWRRH PQLQRVEMNF ISLFWPSLPT GIQAAYEDFD RDLIFLFKGN QYWALSGYDI LQGYPKDISN YGFPSSVQAI DAAVFYRSKT YFFVNDQFWR YDNQRQFMEP GYPKSISGAF PGIESKVDAV FQQEHFFHVF SGPRYYAFDL IAQRVTRVAR GNKWLNCRYG

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

P22894

Internal Search Terms :

MMP8, neutrophil collagenase preproprotein, CLG1, HNC, MMP-8, PMNL-CL,ATGP2543-10ug,ATGP2543-20ug,ATGP2543-50ug,ATGP2543-100ug,ATGP2543-250ug,ATGP2543-500ug,ATGP2543-1mg,ATGP2543-10,ATGP2543-20,ATGP2543-50,ATGP2543-100,ATGP2543-250,ATGP2543-500,ATGP2543-1

more info or order :

NKMAX product webpage