Recombinant human Complement Factor B protein | NKMAX ATGP2541 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human Complement Factor B protein

catalog :

ATGP2541

quantity :

20 ug

price :

80 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human Complement Factor B protein

Domain :

26-259aa

Catalog number (SKU) :

ATGP2541

NCBI :

NP_001701

Description :

CFB is complement factor B, a component of the alternative pathway of complement activation. Factor B circulates in the blood as a single chain polypeptide. upon activation of the alternative pathway, it is cleaved by complement factor D yielding the noncatalytic chain Ba and the catalytic subunit Bb. The active subunit Bb is a serine protease which associates with C3b to form the alternative pathway C3 convertase. Bb is involved in the proliferation of preactivated B lymphocytes, while Ba inhibits their proliferation. Recombinant human CFB protein, fused to His-tag at N-terminus, was expressed in E. coli.

Alternative Names :

complement factor B preproprotein, AHuS4, BF, BFD, CFAB, FB, FBI12, GBG, H2-Bf, PBF2

Concentration :

1mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 0.4M urea

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Mejia J.E., et al (1994). Hum. Immunol. 39:49-53;; Schwaeble W., et al (1993). Immunobiology 188:221-232;;

Purity :

> 85% by SDS-PAGE

Applications :

SDS-PAGE,Denatured

Antigen Species :

Human

Gene Category :

Immunology

Molecular Weight :

28.4 kDa (257aa)

Amino Acid Sequence :

MGSSHHHHHH SSGLVPRGSQ SHMTPWSLAR PQGSCSLEGV EIKGGSFRLL QEGQALEYVC PSGFYPYPVQ TRTCRSTGSW STLKTQDQKT VRKAECRAIH CPRPHDFENG EYWPRSPYYN VSDEISFHCY DGYTLRGSAN RTCQVNGRWS GQTAICDNGA GYCSNPGIPI GTRKVGSQYR LEDSVTYHCS RGLTLRGSQR RTCQEGGSWS GTEPSCQDSF MYDTPQEVAE AFLSSLTETI EGVDAEDGHG PGEQQKR

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

P00751

Internal Search Terms :

Complement Factor B, complement factor B preproprotein, AHuS4, BF, BFD, CFAB, FB, FBI12, GBG, H2-Bf, PBF2,ATGP2541-10ug,ATGP2541-20ug,ATGP2541-50ug,ATGP2541-100ug,ATGP2541-250ug,ATGP2541-500ug,ATGP2541-1mg,ATGP2541-10,ATGP2541-20,ATGP2541-50,ATGP2541-100,ATGP2541-250,ATGP2541-500,ATGP2541-1

more info or order :

NKMAX product webpage