Recombinant human MMP-13 protein | NKMAX ATGP2540 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human MMP-13 protein

catalog :

ATGP2540

quantity :

10 ug

price :

130 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human MMP-13 protein

Domain :

104-471aa

Catalog number (SKU) :

ATGP2540

NCBI :

NP_002418.1

Description :

MMP13 of the matrix metalloproteinase (MMP) family is involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The protein encoded by this gene cleaves type II collagen more efficiently than types I and III. It may be involved in articular cartilage turnover and cartilage pathophysiology associated with osteoarthritis. Recombinant human MMP13 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Alternative Names :

collagenase 3 preproprotein, collagenase 3 preproprotein, CLG3, MANDP1

Concentration :

0.5mg/ml (determined by absorbance at 280nm)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 0.15M NaCl, 1mM DTT

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Gomis-Rueth F.-X., et al (1996). J. Mol. Biol. 264:556-566;; Lausch E., et al (2009). Am. J. Hum. Genet. 85:168-178;;

Purity :

> 85% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Cancer

Molecular Weight :

44.7 kDa (391aa) confirmed by MALDI-TOF

Amino Acid Sequence :

YNVFPRT LKWSKMNLTY RIVNYTPDMT HSEVEKAFKK AFKVWSDVTP LNFTRLHDGI ADIMISFGIK EHGDFYPFDG PSGLLAHAFP PGPNYGGDAH FDDDETWTSS SKGYNLFLVA AHEFGHSLGL DHSKDPGALM FPIYTYTGKS HFMLPDDDVQ GIQSLYGPGD EDPNPKHPKT PDKCDPSLSL DAITSLRGET MIFKDRFFWR LHPQQVDAEL FLTKSFWPEL PNRIDAAYEH PSHDLIFIFR GRKFWALNGY DILEGYPKKI SELGLPKEVK KISAAVHFED TGKTLLFSGN QVWRYDDTNH IMDKDYPRLI EEDFPGIGDK VDAVYEKNGY IYFFNGPIQF EYSIWSNRIV RVMPANSILW C

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

P45452

Internal Search Terms :

MMP13, collagenase 3 preproprotein, collagenase 3 preproprotein, CLG3, MANDP1,ATGP2540-10ug,ATGP2540-20ug,ATGP2540-50ug,ATGP2540-100ug,ATGP2540-250ug,ATGP2540-500ug,ATGP2540-1mg,ATGP2540-10,ATGP2540-20,ATGP2540-50,ATGP2540-100,ATGP2540-250,ATGP2540-500,ATGP2540-1

more info or order :

NKMAX product webpage