Recombinant human Chondromodulin/LECT1 protein | NKMAX ATGP2536 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human Chondromodulin/LECT1 protein

catalog :

ATGP2536

quantity :

20 ug

price :

105 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human Chondromodulin/LECT1 protein

Domain :

214-333aa

Catalog number (SKU) :

ATGP2536

NCBI :

NP_001011705

Description :

LECT1 is a glycosylated transmembrane protein that is cleaved to form a mature, secreted protein. The N-terminus of the precursor protein shares characteristics with other surfactant proteins and is sometimes called chondrosurfactant protein although no biological activity has yet been defined for it. The C-terminus of the precursor protein contains a 25 kDa mature protein called leukocyte cell-derived chemotaxin-1 or chondromodulin-1. The mature protein promotes chondrocyte growth and inhibits angiogenesis. This gene is expressed in the avascular zone of prehypertrophic cartilage and its expression decreases during chondrocyte hypertrophy and vascular invasion. The mature protein likely plays a role in endochondral bone development by permitting cartilaginous anlagen to be vascularized and replaced by bone. Recombinant human LECT1 protein, fused to His-tag at N-terminus, was expressed in E. coli

Alternative Names :

Leukocyte cell-derived chemotaxin 1 isoform 2, BRICD3, CHM-I, CHM1, MYETS1, CNMD, LECT1, Multiple myeloma tumor suppressor 1, BRICHOS domain containing 3

Concentration :

1mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.4M uREA, 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Aoyama,T., et al. (2010) J. Biol. Chem. 285 (39), 29842-29850;; Miura,S., et al. (2010) Exp. Cell Res. 316 (5), 775-788;;

Purity :

> 85% by SDS-PAGE

Applications :

SDS-PAGE, Denatured

Antigen Species :

Human

Gene Category :

Cancer

Molecular Weight :

16.2 kDa (143aa)

Amino Acid Sequence :

MGSSHHHHHH SSGLVPRGSH MGSREVVRKI VPTTTKRPHS GPRSNPGAGR LNNETRPSVQ EDSQAFNPDN PYHQEGESMT FDPRLDHEGI CCIECRRSYT HCQKICEPLG GYYPWPYNYQ GCRSACRVIM PCSWWVARIL GMV

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

O75829

Internal Search Terms :

LECT1, leukocyte cell-derived chemotaxin 1 isoform 2 precursor, leukocyte cell-derived chemotaxin 1 isoform 2 precursor, BRICD3, CHM-I, CHM1, MYETS1,ATGP2536-10ug,ATGP2536-20ug,ATGP2536-50ug,ATGP2536-100ug,ATGP2536-250ug,ATGP2536-500ug,ATGP2536-1mg,ATGP2536-10,ATGP2536-20,ATGP2536-50,ATGP2536-100,ATGP2536-250,ATGP2536-500,ATGP2536-1

more info or order :

NKMAX product webpage