Recombinant human Endoglin/CD105 protein | NKMAX ATGP2525 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human Endoglin/CD105 protein

catalog :

ATGP2525

quantity :

4 ug

price :

80 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human Endoglin/CD105 protein

Domain :

26-586aa

Catalog number (SKU) :

ATGP2525

NCBI :

AAH14271

Description :

ENG is a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds to the beta1 and beta3 peptides with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. This gene may also be involved in preeclampsia and several types of cancer. Recombinant human ENG prtoein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Alternative Names :

Endoglin, END, ORW, HHT1, ORW1, CD105, FLJ41744, ENG, Osler-Rendu-Weber syndrome 1

Concentration :

0.25mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol, 1mM DTT

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Lee N.Y., et al. (2007) J. Biol. Chem. 282:21507-21517

Purity :

> 85% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Stem cell

Molecular Weight :

64.9 kDa (594aa)

Amino Acid Sequence :

ETVH CDLQPVGPER DEVTYTTSQV SKGCVAQAPN AILEVHVLFL EFPTGPSQLE LTLQASKQNG TWPREVLLVL SVNSSVFLHL QALGIPLHLA YNSSLVTFQE PPGVNTTELP SFPKTQILEW AAERGPITSA AELNDPQSIL LRLGQAQGSL SFCMLEASQD MGRTLEWRPR TPALVRGCHL EGVAGHKEAH ILRVLPGHSA GPRTVTVKVE LSCAPGDLDA VLILQGPPYV SWLIDANHNM QIWTTGEYSF KIFPEKNIRG FKLPDTPQGL LGEARMLNAS IVASFVELPL ASIVSLHASS CGGRLQTSPA PIQTTPPKDT CSPELLMSLI QTKCADDAMT LVLKKELVAH LKCTITGLTF WDPSCEAEDR GDKFVLRSAY SSCGMQVSAS MISNEAVVNI LSSSSPQRKK VHCLNMDSLS FQLGLYLSPH FLQASNTIEP GQQSFVQVRV SPSVSEFLLQ LDSCHLDLGP EGGTVELIQG RAAKGNCVSL LSPSPEGDPR FSFLLHFYTV PIPKTGTLSC TVALRPKTGS QDQEVHRTVF MRLNIISPDL SGCTSKG

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

P17813

Internal Search Terms :

Endoglin, CD105, Endoglin, END, ORW, HHT1, ORW1, CD105, FLJ41744,ATGP2525-10ug,ATGP2525-20ug,ATGP2525-50ug,ATGP2525-100ug,ATGP2525-250ug,ATGP2525-500ug,ATGP2525-1mg,ATGP2525-10,ATGP2525-20,ATGP2525-50,ATGP2525-100,ATGP2525-250,ATGP2525-500,ATGP2525-1

more info or order :

NKMAX product webpage