Recombinant human RAMP1 protein | NKMAX ATGP2518 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human RAMP1 protein

catalog :

ATGP2518

quantity :

10 ug

price :

105 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human RAMP1 protein

Domain :

27-117aa

Catalog number (SKU) :

ATGP2518

NCBI :

NP_005846

Description :

RAMP is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. In the presence of this (RAMP1) protein, CRLR functions as a CGRP receptor. The RAMP1 protein is involved in the terminal glycosylation, maturation, and presentation of the CGRP receptor to the cell surface. Recombinant human RAMP1 protein, fused to His-tag at N-terminus, was expressed in E. coli.

Alternative Names :

Receptor activity-modifying protein 1 precursor, CRLR activity-modifying protein 1, Calcitonin-receptor-like receptor activity-modifying protein 1, Receptor activity-modifying protein 1, receptor (G protein-coupled) activity modifying protein 1

Concentration :

0.25mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Kusano S, Kukimoto-Niino M, et al. (2008). Protein Sci. 17(11):1907-14. ;; Heroux M, Hogue M, et al. (2007). J Biol Chem. 282(43):31610-20.;;

Purity :

> 80% by SDS-PAGE

Applications :

SDS-PAGE,Denatured

Antigen Species :

Human

Gene Category :

Signal Transduction

Molecular Weight :

12.9 kDa (114aa)

Amino Acid Sequence :

MGSSHHHHHH SSGLVPRGSH MGSCQEANYG ALLRELCLTQ FQVDMEAVGE TLWCDWGRTI RSYRELADCT WHMAEKLGCF WPNAEVDRFF LAVHGRYFRS CPISGRAVRD PPGS

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

O60894

Internal Search Terms :

RAMP1, Receptor activity-modifying protein 1 precursor, CRLR activity-modifying protein 1, Calcitonin-receptor-like receptor activity-modifying protein 1, Receptor activity-modifying protein 1, receptor (G protein-coupled) activity modifying protein 1,ATGP2518-10ug,ATGP2518-20ug,ATGP2518-50ug,ATGP2518-100ug,ATGP2518-250ug,ATGP2518-500ug,ATGP2518-1mg,ATGP2518-10,ATGP2518-20,ATGP2518-50,ATGP2518-100,ATGP2518-250,ATGP2518-500,ATGP2518-1

more info or order :

NKMAX product webpage