Recombinant human GSK-3 beta protein | NKMAX ATGP2503 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human GSK-3 beta protein

catalog :

ATGP2503

quantity :

10 ug

price :

105 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human GSK-3 beta protein

Domain :

1-420aa

Catalog number (SKU) :

ATGP2503

NCBI :

NP_001139628

Description :

GSK3B is a serine-threonine kinase, belonging to the glycogen synthase kinase subfamily. It is involved in energy metabolism, neuronal cell development, and body pattern formation. Polymorphisms in this gene have been implicated in modifying risk of Parkinson disease, and studies in mice show that overexpression of this gene may be relevant to the pathogenesis of Alzheimer disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. Recombinant human GSK3B protein, was expressed in E. coli.

Alternative Names :

Glycogen synthase kinase 3 beta isoform 2, GSK-3 beta, Glycogen synthase kinase-3 beta

Concentration :

0.5mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Guo X, Ramirez A, et al. (2008). Genes Dev. 22(1):106-20.;; Espinosa L, Ingles-Esteve J, et al. (2003). J Biol Chem. 278(34):32227-35.

Purity :

> 85% by SDS-PAGE

Applications :

SDS-PAGE, Denatured

Antigen Species :

Human

Gene Category :

Metabolism

Molecular Weight :

46 kDa (420aa)

Amino Acid Sequence :

MSGRPRTTSF AESCKPVQQP SAFGSMKVSR DKDGSKVTTV VATPGQGPDR PQEVSYTDTK VIGNGSFGVV YQAKLCDSGE LVAIKKVLQD KRFKNRELQI MRKLDHCNIV RLRYFFYSSG EKKDEVYLNL VLDYVPETVY RVARHYSRAK QTLPVIYVKL YMYQLFRSLA YIHSFGICHR DIKPQNLLLD PDTAVLKLCD FGSAKQLVRG EPNVSYICSR YYRAPELIFG ATDYTSSIDV WSAGCVLAEL LLGQPIFPGD SGVDQLVEII KVLGTPTREQ IREMNPNYTE FKFPQIKAHP WTKVFRPRTP PEAIALCSRL LEYTPTARLT PLEACAHSFF DELRDPNVKL PNGRDTPALF NFTTQELSSN PPLATILIPP HARIQAAAST PTNATAASDA NTGDRGQTNN AASASASNST

Tag :

Non-Tagged

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

P49841

Internal Search Terms :

GSK3 b, Glycogen synthase kinase 3 beta isoform 2, GSK-3 beta, Glycogen synthase kinase-3 beta,ATGP2503-10ug,ATGP2503-20ug,ATGP2503-50ug,ATGP2503-100ug,ATGP2503-250ug,ATGP2503-500ug,ATGP2503-1mg,ATGP2503-10,ATGP2503-20,ATGP2503-50,ATGP2503-100,ATGP2503-250,ATGP2503-500,ATGP2503-1

more info or order :

NKMAX product webpage