product summary
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company name :
NKMAX
product type :
protein
product name :
Recombinant human CCM2 protein
catalog :
ATGP2496
quantity :
10 ug
price :
80 USD
more info or order :
product information
Product Type :
Proteins
Item Name :
Recombinant human CCM2 protein
Domain :
66-353aa
Catalog number (SKU) :
ATGP2496
NCBI :
NP_001161407
Description :
CCM2 provides instructions for making a protein called malcavernin, which strengthens the interactions between cells that form blood vessels and limits leakage from the vessels. It interacts with a number of other proteins to form a complex that is found in the junctions that connect neighboring cells. It helps turn off (suppress) a signaling molecule known as RhoA-GTPase. Recombinant human CCM2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.
Alternative Names :
Malcavernin isoform 4, Malcavernin isoform 4, Malcavernin isoform 4
Concentration :
0.5mg/ml (determined by Bradford assay)
Formulation :
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 20% glycerol, 1mM DTT
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Dupre N. et al. (2003) Can J Neurol Sci. 30:122-128;; Liquori CL. et al. (2007) Am J Hum Genet. 80:69-75.;;
Purity :
> 90% by SDS-PAGE
Applications :
SDS-PAGE
Antigen Species :
Human
Gene Category :
Signal Transduction
Molecular Weight :
34.3 kDa (311aa) confirmed by MALDI-TOF
Amino Acid Sequence :
EVKYLGQ LTSIPGYLNP SSRTEILHFI DNAKRAHQLP GHLTQEHDAV LSLSAYNVKL AWRDGEDIIL RVPIHDIAAV SYVRDDAAHL VVLKTDDSST KVDIKETYEV EASTFCFPES VDVGGASPHS KTISESELSA SATELLQDYM LTLRTKLSSQ EIQQFAALLH EYRNGASIHE FCINLRQLYG DSRKFLLLGL RPFIPEKDSQ HFENFLETIG VKDGRGIITD SFGRHRRALS TTSSSTTNGN RATGSSDDRS APSEGDEWDR MISDISSDIE ALGCSMDQDS A
Tag :
His-Tag
Expression System :
E.coli
Product Type Name :
Recombinant Protein
UniProt No. :
Q9BSQ5
Internal Search Terms :
CCM2, Malcavernin isoform 4, Malcavernin isoform 4, Malcavernin isoform 4,ATGP2496-10ug,ATGP2496-20ug,ATGP2496-50ug,ATGP2496-100ug,ATGP2496-250ug,ATGP2496-500ug,ATGP2496-1mg,ATGP2496-10,ATGP2496-20,ATGP2496-50,ATGP2496-100,ATGP2496-250,ATGP2496-500,ATGP2496-1
more info or order :
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.