Recombinant human Complement Factor B protein | NKMAX ATGP2479 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human Complement Factor B protein

catalog :

ATGP2479

quantity :

20 ug

price :

80 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human Complement Factor B protein

Domain :

260-764aa

Catalog number (SKU) :

ATGP2479

NCBI :

NP_001701

Description :

CFB encodes complement factor B, a component of the alternative pathway of complement activation. Factor B circulates in the blood as a single chain polypeptide. upon activation of the alternative pathway, it is cleaved by complement factor D yielding the noncatalytic chain Ba and the catalytic subunit Bb. The active subunit Bb is a serine protease which associates with C3b to form the alternative pathway C3 convertase. Bb is involved in the proliferation of preactivated B lymphocytes, while Ba inhibits their proliferation. Recombinant human CFB-Bb protein, fused to His-tag at N-terminus, was expressed in E. coli.

Alternative Names :

complement factor B, AHuS4, BF, BFD, CFAB, FB, FBI12, GBG, H2-Bf, PBF2

Concentration :

1mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Wu,L., et al. (2013) Invest. Ophthalmol. Vis. Sci. 54 (1), 170-174;; Thakkinstian,A., et al. (2012) Am. J. Epidemiol. 176 (5), 361-372;;

Purity :

> 85% by SDS-PAGE

Applications :

SDS-PAGE, Denatured

Antigen Species :

Human

Gene Category :

Immunology

Molecular Weight :

59.4 kDa (528aa)

Amino Acid Sequence :

KIVLDPS GSMNIYLVLD GSDSIGASNF TGAKKCLVNL IEKVASYGVK PRYGLVTYAT YPKIWVKVSE ADSSNADWVT KQLNEINYED HKLKSGTNTK KALQAVYSMM SWPDDVPPEG WNRTRHVIIL MTDGLHNMGG DPITVIDEIR DLLYIGKDRK NPREDYLDVY VFGVGPLVNQ VNINALASKK DNEQHVFKVK DMENLEDVFY QMIDESQSLS LCGMVWEHRK GTDYHKQPWQ AKISVIRPSK GHESCMGAVV SEYFVLTAAH CFTVDDKEHS IKVSVGGEKR DLEIEVVLFH PNYNINGKKE AGIPEFYDYD VALIKLKNKL KYGQTIRPIC LPCTEGTTRA LRLPPTTTCQ QQKEELLPAQ DIKALFVSEE EKKLTRKEVY IKNGDKKGSC ERDAQYAPGY DKVKDISEVV TPRFLCTGGV SPYADPNTCR GDSGGPLIVH KRSRFIQVGV ISWGVVDVCK NQKRQKQVPA HARDFHINLF QVLPWLKEKL QDEDLGFL

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

P00751

Internal Search Terms :

Complement Factor B, complement factor B, AHuS4, BF, BFD, CFAB, FB, FBI12, GBG, H2-Bf, PBF2,ATGP2479-10ug,ATGP2479-20ug,ATGP2479-50ug,ATGP2479-100ug,ATGP2479-250ug,ATGP2479-500ug,ATGP2479-1mg,ATGP2479-10,ATGP2479-20,ATGP2479-50,ATGP2479-100,ATGP2479-250,ATGP2479-500,ATGP2479-1

more info or order :

NKMAX product webpage