product summary
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company name :
NKMAX
product type :
protein
product name :
Recombinant human NRG4 protein
catalog :
ATGP2472
quantity :
10 ug
price :
105 USD
more info or order :
product information
Product Type :
Proteins
Item Name :
Recombinant human NRG4 protein
Domain :
1-61aa
Catalog number (SKU) :
ATGP2472
NCBI :
NP_612640
Description :
NRG4 belongs to the neuregulin family and contains 1 EGF-like domain. The protein is low affinity ligand for the ERBB4 tyrosine kinase receptor. It concomitantly recruits ERBB1 and ERBB2 coreceptors, resulting in ligand-stimulated tyrosine phosphorylation and activation of the ERBB receptors. NRG4 does not bind to the ERBB1, ERBB2 and ERBB3 receptors. Recombinant human NRG4 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Alternative Names :
Pro-neuregulin-4 membrane-bound isoform, Pro-neuregulin-4, membrane-bound isoform, Neuregulin 4, HRG4
Concentration :
0.25mg/ml (determined by Bradford assay)
Formulation :
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 30% glycerol, 0.15M NaCl, 1mM DTT
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Zody M.C., Garber M et al. (2006), Nature 440:671-675
Purity :
> 90% by SDS-PAGE
Applications :
SDS-PAGE
Antigen Species :
Human
Gene Category :
Signal Transduction
Molecular Weight :
9.1 kDa (84aa) confirmed by MALDI-TOF
Amino Acid Sequence :
MGSSHHHHHH SSGLVPRGSH MGSMPTDHEE PCGPSHKSFC LNGGLCYVIP TIPSPFCRCV ENYTGARCEE VFLPGSSIQT KSNL
Tag :
His-Tag
Expression System :
E.coli
Product Type Name :
Recombinant Protein
UniProt No. :
Q8WWG1
Internal Search Terms :
NRG4, Pro-neuregulin-4 membrane-bound isoform, Pro-neuregulin-4, membrane-bound isoform, Neuregulin 4, HRG4,ATGP2472-10ug,ATGP2472-20ug,ATGP2472-50ug,ATGP2472-100ug,ATGP2472-250ug,ATGP2472-500ug,ATGP2472-1mg,ATGP2472-10,ATGP2472-20,ATGP2472-50,ATGP2472-100,ATGP2472-250,ATGP2472-500,ATGP2472-1
more info or order :
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.