Recombinant human NDUFS2 protein | NKMAX ATGP2463 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human NDUFS2 protein

catalog :

ATGP2463

quantity :

4 ug

price :

80 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human NDUFS2 protein

Domain :

77-463aa

Catalog number (SKU) :

ATGP2463

NCBI :

NP_004541

Description :

NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial isoform 1 precursor, also known as NDUFS2, is a 463 amino acid protein that is suggested to be required for catalytic activity. Defects in NDuFS2 are the cause of complex I mitochondrial respiratory chain deficiency, which is characterized by a variety of symptoms including liver failure, cardiomyopathy and neurodegeneration. Located in the mitochondrial inner membrane, mitochondrial complex I is the first and largest enzyme in the electron transport chain of oxidative phosphorylation. Recombinant human NDUFS2 protein, fused to His-tag at N-terminus, was expressed in E. coli.

Alternative Names :

NADH:ubiquinone oxidoreductase core subunit S2, NADH dehydrogenase [ubiquinone] iron-sulfur protein 2 mitochondrial, NADH dehydrogenase (ubiquinone) Fe-S protein 2, NADH-coenzyme Q reductase, Complex I-49kD, CI-49kD, NADH-ubiquinone oxidoreductase 49 kDa subunit, complex I 49kDa subunit, CI-49

Concentration :

0.25mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Loeffen J., et al. (2001) Ann Neurol. 49:195-201.;; Procaccio V., et al. (1998) Genome. 9:482-484.;;

Purity :

> 80% by SDS-PAGE

Applications :

SDS-PAGE, Denatured

Antigen Species :

Human

Gene Category :

Metabolism

Molecular Weight :

46.5 kDa (410aa)

Amino Acid Sequence :

VKNITLN FGPQHPAAHG VLRLVMELSG EMVRKCDPHI GLLHRGTEKL IEYKTYLQAL PYFDRLDYVS MMCNEQAYSL AVEKLLNIRP PPRAQWIRVL FGEITRLLNH IMAVTTHALD LGAMTPFFWL FEEREKMFEF YERVSGARMH AAYIRPGGVH QDLPLGLMDD IYQFSKNFSL RLDELEELLT NNRIWRNRTI DIGVVTAEEA LNYGFSGVML RGSGIQWDLR KTQPYDVYDQ VEFDVPVGSR GDCYDRYLCR VEEMRQSLRI IAQCLNKMPP GEIKVDDAKV SPPKRAEMKT SMESLIHHFK LYTEGYQVPP GATYTAIEAP KGEFGVYLVS DGSSRPYRCK IKAPGFAHLA GLDKMSKGHM LADVVAIIGT QDIVFGEVDR

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

O75306

Internal Search Terms :

NDuFS2, NADH dehydrogenase [ubiquinone] iron-sulfur protein 2 mitochondrial isoform 1 precursor, NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial isoform 1 precursor, CI-49,ATGP2463-10ug,ATGP2463-20ug,ATGP2463-50ug,ATGP2463-100ug,ATGP2463-250ug,ATGP2463-500ug,ATGP2463-1mg,ATGP2463-10,ATGP2463-20,ATGP2463-50,ATGP2463-100,ATGP2463-250,ATGP2463-500,ATGP2463-1

more info or order :

NKMAX product webpage